QuickView for tgat (gene)

Gene Symbol:

TRIO Homo sapiens

Full name:

trio Rho guanine nucleotide exchange factor

Synonyms:

ARHGEF23, MEBAS, MRD44, tgat, triple functional domain protein, PTPRF-interacting protein, triple functional domain (PTPRF interacting)

Genomic Location:

Chr 5: 14196829-14562458

Description:

This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants.

This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367 ,  GCAAAAA_MIR129 ,  ATACTGT_MIR144

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-539

Cytogenetic Map:

5p15.2

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