QuickView for thromboxane receptor (gene)
- Gene Symbol:
- Tbxa2r
Rattus norvegicus - Full name:
- thromboxane A2 receptor
- Synonyms:
- thromboxane A2 receptor, TXA2-R, TXR2, Thromboxane receptor, prostanoid TP receptor
- Genomic Location:
- Chr 7: 9867739-9872536
- Description:
-
binds thromboxane and induces an increase in cytosolic Ca2+ levels; may play a role renal electrolyte metabolism; may mediate vascular smooth muscle cell contraction and proliferation
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
GO Molecular Function
transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity | thromboxane receptor activity | protein binding
GO Biological Process
response to extracellular stimulus | regulation of blood vessel diameter | regulation of muscle system process | response to nutrient levels | positive regulation of blood circulation | response to lipopolysaccharide | intracellular signal transduction | regulation of localization | response to hormone | negative regulation of cellular process | positive regulation of developmental process | negative regulation of cell migration involved in sprouting angiogenesis | defense response | regulation of smooth muscle contraction | response to drug | regulation of sprouting angiogenesis | cellular chemical homeostasis | response to antibiotic | cellular process | regulation of cell motility | cellular homeostasis | positive regulation of blood coagulation | negative regulation of cell migration | positive regulation of vasoconstriction | negative regulation of cell motility | regulation of angiogenesis | regulation of cellular process | cellular response to lipid | regulation of cytosolic calcium ion concentration | cellular response to molecule of bacterial origin | calcium ion homeostasis | G-protein coupled receptor activity | regulation of vasculature development | response to stimulus | positive regulation of blood pressure | regulation of blood vessel size | response to stress | negative regulation of angiogenesis | regulation of blood circulation | response to alcohol | response to molecule of bacterial origin | blood circulation | G-protein coupled receptor signaling pathway | regulation of wound healing | metal ion homeostasis | response to ethanol | water homeostasis | response to external biotic stimulus | positive regulation of response to wounding | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of muscle contraction | response to ketone | response to lipid | regulation of blood pressure | thromboxane A2 signaling pathway | cellular ion homeostasis | regulation of blood coagulation | positive regulation of cytosolic calcium ion concentration | regulation of cell migration | regulation of cellular component movement | response to nutrient | regulation of cell migration involved in sprouting angiogenesis | regulation of endothelial cell migration | thromboxane receptor activity | second-messenger-mediated signaling | negative regulation of epithelial cell migration | response to toxic substance | cation homeostasis | response to bacterium | negative regulation of blood vessel endothelial cell migration | cellular cation homeostasis | cell communication | positive regulation of smooth muscle contraction | response to testosterone | inflammatory response | cyclic-nucleotide-mediated signaling | cellular calcium ion homeostasis | homeostatic process | regulation of locomotion | regulation of tube size | negative regulation of sprouting angiogenesis | response to organic substance | cAMP-mediated signaling | regulation of vasoconstriction | regulation of body fluid levels | positive regulation of coagulation | regulation of tube diameter | chemical homeostasis | positive regulation of muscle contraction | negative regulation of cellular component movement | ion homeostasis | positive regulation of wound healing | regulation of epithelial cell migration | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of response to wounding | regulation of blood vessel endothelial cell migration | signaling | response to organic cyclic compound | response to biotic stimulus | regulation of developmental process | negative regulation of vasculature development | negative regulation of endothelial cell migration | cellular metal ion homeostasis | cellular response to organic substance | divalent inorganic cation homeostasis | negative regulation of locomotion | positive regulation of angiogenesis | response to other organism | signal transduction | cellular response to lipopolysaccharide | multicellular organismal process
GO Cellular Component
secretory granule | integral component of membrane | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | nuclear lumen | intrinsic component of membrane | cytoplasm | acrosomal vesicle | intracellular organelle | nuclear body | secretory vesicle | endomembrane system | nucleoplasm | plasma membrane | nuclear speck | vesicle | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | intracellular vesicle | intracellular | membrane
