Name: | Transforming Growth Factor beta2 |
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Description: | A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. |
Synonyms: |
TGF-beta-2; TGF-beta2; Cartilage Inducing Factor B; BSC 1 Cell Growth Inhibitor; Polyergin; Suppressor Factor, T-Cell, Glioblastoma-Derived; Cartilage-Inducing Factor-B; Glioblastoma-Derived T-Cell Suppressor Factor; BSC-1 Cell Growth Inhibitor; Glioblastoma Derived T Cell Suppressor Factor
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