QuickView for transforming growth factor beta (compound)

Name:	Transforming Growth Factor beta
Description:	A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Synonyms:	Bone Derived Transforming Growth Factor; Platelet Transforming Growth Factor; TGF-beta; Milk Growth Factor; Bone-Derived Transforming Growth Factor; Growth Factor, Milk; Factor, Milk Growth; TGFbeta