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QuickView for vascular endothelial growth factor c (gene)


Gene Symbol:
VEGFC Homo sapiens Homo sapiens
Full name:
vascular endothelial growth factor C
Synonyms:
Flt4-L, LMPH1D, VRP, vascular endothelial growth factor C, FLT4 ligand DHM, vascular endothelial growth factor-related protein
Genomic Location:
Chr 4: 177841685-177950889
Description:
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activa...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 4
4q34.3


Transcripts Names
NM_005429
Protein Names
P49767
B2R9Q8



GO Molecular Function

signaling receptor binding | cytokine receptor binding | molecular function regulator | vascular endothelial growth factor receptor 3 binding | vascular endothelial growth factor receptor binding | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | chemoattractant activity | growth factor receptor binding

GO Biological Process

regulation of leukocyte chemotaxis | positive regulation of locomotion | exocytosis | response to cytokine | cell motility | regulation of neurogenesis | regulation of cell development | regulation of localization | morphogenesis of an epithelium | induction of positive chemotaxis | positive regulation of peptidyl-tyrosine phosphorylation | establishment of localization | regulation of immune system process | platelet degranulation | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | positive regulation of epithelial cell proliferation | nervous system development | response to drug | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | generation of neurons | positive regulation of protein secretion | regulation of neuroblast proliferation | blood vessel morphogenesis | cellular process | secretion | regulation of cell motility | localization | regulation of vascular endothelial growth factor receptor signaling pathway | regulation of chemotaxis | response to hypoxia | response to growth factor | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | tissue development | regulation of cell differentiation | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | epithelium development | regulation of cell division | positive regulation of epithelial cell migration | sprouting angiogenesis | regulation of peptide secretion | regulation of vasculature development | response to stimulus | vasculature development | cellular response to vascular endothelial growth factor stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | positive regulation of neuroblast proliferation | tube morphogenesis | secretion by cell | cardiovascular system development | positive regulation of blood vessel endothelial cell migration | regulation of protein transport | blood circulation | regulation of mast cell chemotaxis | regulation of peptide transport | regulation of cell adhesion | embryo development | positive regulation of cell-matrix adhesion | molecular function regulator | positive chemotaxis | negative regulation of blood pressure | blood vessel development | positive regulation of peptide secretion | locomotion | system development | response to oxygen levels | regulation of signal transduction | multicellular organism development | cell migration | regulation of phosphorylation | positive regulation of chemotaxis | positive regulation of secretion | regulation of blood pressure | regulation of protein autophosphorylation | regulation of stem cell proliferation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | vascular endothelial growth factor signaling pathway | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | enzyme linked receptor protein signaling pathway | vesicle-mediated transport | regulation of cellular component movement | positive regulation of mast cell chemotaxis | positive regulation of cell differentiation | regulation of endothelial cell migration | positive regulation of cell migration | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | angiogenesis | regulated exocytosis | regulation of leukocyte migration | cell communication | regulation of cellular metabolic process | positive regulation of leukocyte chemotaxis | regulation of protein metabolic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of locomotion | positive regulation of lymphangiogenesis | positive regulation of transport | regulation of cellular response to growth factor stimulus | embryonic morphogenesis | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | substrate-dependent cell migration | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | growth factor activity | regulation of neural precursor cell proliferation | positive regulation of cell development | regulation of secretion | morphogenesis of embryonic epithelium | receptor ligand activity | chemoattractant activity | animal organ development | regulation of endothelial cell proliferation | positive regulation of cell-substrate adhesion | regulation of protein secretion | positive regulation of leukocyte migration | regulation of phosphate metabolic process | positive regulation of endothelial cell migration | positive regulation of protein transport | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | regulation of cell communication | regulation of blood vessel endothelial cell migration | cellular response to leukemia inhibitory factor | signaling | regulation of epithelial cell proliferation | positive regulation of phosphorylation | anatomical structure morphogenesis | positive regulation of stem cell proliferation | regulation of nervous system development | regulation of developmental process | positive regulation of neural precursor cell proliferation | developmental process | positive regulation of protein autophosphorylation | vascular endothelial growth factor receptor signaling pathway | tube development | regulation of transport | negative regulation of cell proliferation | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | cellular response to organic substance | regulation of protein localization | positive regulation of cell motility | circulatory system development | chemotaxis | positive regulation of angiogenesis | signal transduction | regulation of signaling | regulation of cell-matrix adhesion | cellular response to growth factor stimulus | multicellular organismal process | positive regulation of positive chemotaxis | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | platelet alpha granule | secretory vesicle | endomembrane system | vesicle | extracellular region | membrane-bounded organelle | organelle | extracellular space | membrane-enclosed lumen | secretory granule lumen | intracellular vesicle | intracellular | membrane | platelet alpha granule lumen | vesicle lumen