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QuickView for vesicular acetylcholine transporter (gene)


Gene Symbol:
SLC18A3 Homo sapiens Homo sapiens
Full name:
solute carrier family 18 member A3
Synonyms:
CMS21, VACHT, vesicular acetylcholine transporter, solute carrier family 18 (vesicular acetylcholine transporter), member 3, solute carrier family 18 (vesicular acetylcholine), member 3, solute carrier family 18, member 3
Genomic Location:
Chr 10: 50488353-50490772
Description:
This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransfera...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 10
10q11.23


Transcripts Names
NM_003055
Protein Names
B2R7S1
Q16572



GO Molecular Function

acetylcholine transmembrane transporter activity | cation binding | ammonium transmembrane transporter activity | neurotransmitter transporter activity | neurotransmitter binding | transmembrane transporter activity | cation transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | organic cation transmembrane transporter activity | acetylcholine binding | drug transmembrane transporter activity | hormone binding | drug binding

GO Biological Process

neurotransmitter secretion | establishment of localization | organic cation transport | response to drug | membrane organization | cellular process | secretion | acetylcholine transmembrane transporter activity | ammonium transmembrane transporter activity | localization | chemical synaptic transmission | neurotransmitter transporter activity | establishment of localization in cell | transmembrane transporter activity | cellular component organization | response to stimulus | cellular localization | secretion by cell | cell-cell signaling | regulation of neurotransmitter levels | ion transmembrane transport | organic substance transport | synaptic signaling | cation transmembrane transporter activity | ion transmembrane transporter activity | acetate ester transport | organic cation transmembrane transporter activity | cell communication | drug transmembrane transporter activity | cation transmembrane transport | ammonium transmembrane transport | drug transport | transmembrane transport | signaling | drug transmembrane transport | cation transport | ammonium transport | neurotransmitter transport | signal release | ion transport

GO Cellular Component

clathrin coat of endocytic vesicle | integral component of membrane | intracellular membrane-bounded organelle | synapse | neuron projection | clathrin-coated endocytic vesicle membrane | endocytic vesicle membrane | clathrin-coated vesicle membrane | organelle membrane | vesicle coat | clathrin-coated vesicle | clathrin coat of coated pit | cytoplasmic vesicle | Golgi-associated vesicle membrane | cell | plasma membrane protein complex | distal axon | intrinsic component of membrane | terminal bouton | AP-2 adaptor complex | transport vesicle membrane | cytoplasm | clathrin-coated endocytic vesicle | intracellular organelle | clathrin coat of trans-Golgi network vesicle | clathrin-sculpted acetylcholine transport vesicle membrane | AP-type membrane coat adaptor complex | presynapse | Golgi apparatus | protein-containing complex | cell projection | clathrin adaptor complex | endomembrane system | plasma membrane | Golgi-associated vesicle | vesicle | transport vesicle | clathrin-coated pit | coated vesicle membrane | membrane-bounded organelle | clathrin coat | organelle | vesicle membrane | axon terminus | cell periphery | axon | clathrin vesicle coat | trans-Golgi network transport vesicle membrane | trans-Golgi network transport vesicle | neuron projection terminus | intracellular vesicle | endocytic vesicle | intracellular | AP-1 adaptor complex | membrane | cytoplasmic vesicle membrane | membrane coat | coated vesicle