QuickView for zfat (gene)

Gene Symbol:

ZFAT Homo sapiens

Full name:

zinc finger and AT-hook domain containing

Synonyms:

AITD3, ZFAT1, ZNF406, zinc finger protein ZFAT, zinc finger gene in autoimmune thyroid disease, zinc finger protein 406, zinc-finger gene in AITD susceptibility region

Genomic Location:

Chr 8: 135559213-135794463

Description:

This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GCCATNTTG_YY1_Q6 ,  CACCAGC_MIR138 ,  YY1_02 ,  KMCATNNWGGA_UNKNOWN

Cytogenetic Map:

8q24.22

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