QuickView for 4E-BP1;jsessionid=B19100D5F9D2BC80DCC443F54FD8B2EB;jsessionid=4022B0623EE82961AA534087423D8069 (gene)
- Gene Symbol:
- Eif4ebp1
Rattus norvegicus - Full name:
- eukaryotic translation initiation factor 4E binding protein 1
- Synonyms:
- PHAS-I, eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, phosphorylated heat- and acid-stable protein regulated by insulin 1
- Genomic Location:
- Chr 16: 69110522-69123895
- Description:
-
forms a complex with eukaryotic initiation factor-4E (eIF-4E) and is anintracellular target for insulin and growth factors
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
translation initiation factor binding | eukaryotic initiation factor 4E binding | protein phosphatase 2A binding | enzyme binding | translation repressor activity | protein binding | protein phosphatase binding | translation regulator activity | phosphatase binding
GO Biological Process
response to extracellular stimulus | cellular response to decreased oxygen levels | response to nutrient levels | intracellular signal transduction | response to hormone | negative regulation of cellular process | response to dexamethasone | respiratory tube development | response to drug | response to antibiotic | cellular process | TOR signaling | response to hypoxia | regulation of cell cycle | negative regulation of cellular metabolic process | response to peptide hormone | regulation of cellular process | cellular response to lipid | regulation of metabolic process | regulation of protein complex assembly | cellular response to organonitrogen compound | IRES-dependent translational initiation of linear mRNA | regulation of translational initiation | response to stimulus | peptide biosynthetic process | respiratory system development | cellular response to xenobiotic stimulus | cellular response to hypoxia | response to stress | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | response to peptide | response to starvation | response to alcohol | cellular nitrogen compound metabolic process | response to ischemia | cell cycle G1/S phase transition | cellular response to organic cyclic compound | negative regulation of metabolic process | cellular biosynthetic process | translational initiation | response to ethanol | response to nitrogen compound | cellular response to hormone stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | multicellular organism development | cellular response to peptide hormone stimulus | cap-independent translational initiation | cellular response to insulin stimulus | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | response to ketone | cellular response to stress | response to lipid | cellular response to peptide | cell cycle | insulin receptor signaling pathway | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | response to corticosteroid | cellular amide metabolic process | translation | biosynthetic process | regulation of cellular protein metabolic process | cellular response to glucocorticoid stimulus | response to toxic substance | translation repressor activity | response to xenobiotic stimulus | mitotic cell cycle phase transition | cellular response to corticosteroid stimulus | cellular response to drug | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | G1/S transition of mitotic cell cycle | peptide metabolic process | regulation of mitotic cell cycle | protein metabolic process | response to organic substance | translation regulator activity | response to antineoplastic agent | response to insulin | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | metabolic process | negative regulation of protein complex assembly | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | gene expression | amide biosynthetic process | cellular response to steroid hormone stimulus | negative regulation of translation | lung development | cellular response to dexamethasone stimulus | negative regulation of protein metabolic process | signaling | response to organic cyclic compound | cellular protein metabolic process | cellular macromolecule biosynthetic process | negative regulation of translational initiation | developmental process | cytoplasmic translational initiation | tube development | response to organonitrogen compound | cell cycle phase transition | response to amino acid starvation | transmembrane receptor protein tyrosine kinase signaling pathway | cytoplasmic translation | cellular metabolic process | cellular response to organic substance | response to steroid hormone | regulation of translation | regulation of cellular component organization | signal transduction | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | protein-containing complex | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
