QuickView for ABCB11;jsessionid=B4F1C9E65DC03F2F3B1A12A61641CE19;jsessionid=3BE3055C4D64D5982BEA6786490AF817 (gene)
- Gene Symbol:
- Abcb11
Rattus norvegicus - Full name:
- ATP binding cassette subfamily B member 11
- Synonyms:
- Bsep, Spgp, bile salt export pump, ATP-binding cassette sub-family B member 11, ATP-binding cassette, sub-family B (MDR/TAP), member 11, ATP-binding cassette, subfamily B (MDR/TAP), member 11, sister of P-glycoprotein
- Genomic Location:
- Chr 3_random: 424599-689697
- Description:
-
acts as an ATP-dependent bile salt export pump; transports taurochenodeoxycholate, taurocholate, and other bile salts
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
bile acid transmembrane transporter activity | ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | anion transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | organic acid transmembrane transporter activity | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | drug transmembrane transporter activity | carboxylic acid transmembrane transporter activity | canalicular bile acid transmembrane transporter activity | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | monocarboxylic acid transmembrane transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
bile acid transmembrane transporter activity | lipid transport | ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | response to drug | secretion | monocarboxylic acid transport | localization | anion transport | macromolecule localization | transmembrane transporter activity | canalicular bile acid transport | drug export | response to stimulus | acid secretion | response to stress | organic acid transmembrane transporter activity | organic hydroxy compound transport | carboxylic acid transmembrane transport | ion transmembrane transport | organic substance transport | active transmembrane transporter activity | response to oxidative stress | organic acid transport | ion transmembrane transporter activity | organic anion transport | response to estrogen | drug transmembrane transporter activity | carboxylic acid transmembrane transporter activity | canalicular bile acid transmembrane transporter activity | anion transmembrane transport | organic acid transmembrane transport | lipid localization | bile acid and bile salt transport | monocarboxylic acid transmembrane transporter activity | drug transport | transmembrane transport | drug transmembrane transport | carboxylic acid transport | lipid transporter activity | ion transport
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | apical plasma membrane | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intercellular canaliculus | intracellular organelle | apical part of cell | cell-cell junction | Golgi apparatus | endomembrane system | plasma membrane | Golgi membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | cell junction | membrane
