QuickView for ACTA2;jsessionid=1D6A8A10A2A88063DDD90935772DCACA;jsessionid=AD80EB74E1C9681325F67A38C253FF8A (gene)
- Gene Symbol:
- Acta2
Mus musculus - Full name:
- actin, alpha 2, smooth muscle, aorta
- Synonyms:
- 0610041G09Rik, Actvs, SMalphaA, a-SMA, alphaSMA, actin, aortic smooth muscle, actin, alpha, vascular smooth muscle, alpha-actin-2
- Genomic Location:
- Chr 19: 34315581-34329826
- Description:
-
The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the...
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
GO Molecular Function
kinase binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of ERK1 and ERK2 cascade | regulation of blood vessel diameter | positive regulation of locomotion | regulation of localization | vascular smooth muscle contraction | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | regulation of fibroblast migration | regulation of cell motility | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of actin filament-based movement | positive regulation of cellular protein metabolic process | smooth muscle contraction | muscle contraction | positive regulation of protein metabolic process | regulation of blood vessel size | positive regulation of cell activation | positive regulation of fibroblast migration | blood circulation | regulation of wound healing | negative regulation of blood vessel diameter | regulation of signal transduction | regulation of MAPK cascade | regulation of phosphorylation | regulation of blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of hepatic stellate cell activation | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of intracellular signal transduction | regulation of cellular component movement | positive regulation of cell migration | regulation of cellular protein metabolic process | vasoconstriction | positive regulation of hepatic stellate cell migration | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | regulation of locomotion | regulation of tube size | positive regulation of hepatic stellate cell activation | positive regulation of protein modification process | regulation of intracellular signal transduction | regulation of tube diameter | regulation of cell activation | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | positive regulation of MAPK cascade | regulation of response to wounding | regulation of cell communication | positive regulation of phosphorylation | positive regulation of hepatic stellate cell contraction | positive regulation of metabolic process | regulation of actin filament-based process | positive regulation of cell motility | muscle system process | positive regulation of signaling | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | cell | smooth muscle contractile fiber | cytoplasm | intracellular organelle | actin cytoskeleton | contractile fiber | actomyosin | organelle | stress fiber | cytoskeleton | intracellular | actin filament bundle | supramolecular complex
