QuickView for ADAMTS7;jsessionid=C8BB72DE11DA1CF226F1046FAE493A3C;jsessionid=ABD881DEEF1EA7CE6E754D5D11B469AA;jsessionid=3A7F639E41B83B3C9FC6394C3A4E08F2 (gene)

Gene Symbol:

Adamts7 Mus musculus

Full name:

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7

Synonyms:

ADAM-TS7, ADAMTS7B, A disintegrin and metalloproteinase with thrombospondin motifs 7, COMPase, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7

Genomic Location:

Chr 9: 90057816-90094940

Description:

This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing ...

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This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent enzyme that degrades cartilage oligomeric matrix protein. The deficiency of the encoded protein decreases atherosclerosis in genetically hyperlipidemic mice and in response to vascular injury. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP3_Q3 ,  TGGNNNNNNKCCAR_UNKNOWN ,  RYTTCCTG_ETS2_B

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-29

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