QuickView for ADRBK2;jsessionid=D39A83E15424545D1D19DEC3AA42EF12;jsessionid=464C76E925F0040CC2C4F99595CE0700 (gene)
- Gene Symbol:
- Grk3
Rattus norvegicus - Full name:
- G protein-coupled receptor kinase 3
- Synonyms:
- Adrbk2, beta-adrenergic receptor kinase 2, adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase), adrenergic, beta, receptor kinase 2, beta ARK2, beta-ARK-2
- Genomic Location:
- Chr Un: 51676370-51727951
- Description:
-
catalzyes phosphorylation of the beta-adrenergic receptor; may mediate desensitizaton of synaptic receptors; may regulate bone formation
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
D1 dopamine receptor binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | G-protein coupled receptor kinase activity | anion binding | adenyl nucleotide binding | dopamine receptor binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | beta-adrenergic receptor kinase activity | transferase activity, transferring phosphorus-containing groups | G-protein coupled receptor binding | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
negative regulation of G-protein coupled receptor protein signaling pathway | response to isoquinoline alkaloid | establishment of localization | negative regulation of cellular process | response to drug | polyol metabolic process | positive regulation of phosphate metabolic process | intracellular transport | cellular process | response to morphine | localization | protein transport | negative regulation of signaling | eye pigmentation | macromolecule localization | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | response to stimulus | positive regulation of protein metabolic process | intracellular protein transport | alcohol metabolic process | protein serine/threonine kinase activity | cellular localization | G-protein coupled receptor signaling pathway | protein modification process | macromolecule modification | organic hydroxy compound metabolic process | response to nitrogen compound | G-protein coupled receptor kinase activity | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | phosphorus metabolic process | regulation of phosphorylation | organic substance transport | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | developmental pigmentation | response to ammonium ion | regulation of nitrogen compound metabolic process | small molecule metabolic process | peptide transport | vesicle-mediated transport | pigmentation | regulation of cellular protein metabolic process | phosphorylation | rhodopsin metabolic process | response to xenobiotic stimulus | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | receptor internalization | regulation of protein metabolic process | regulation of protein phosphorylation | negative adaptation of signaling pathway | protein metabolic process | positive regulation of protein modification process | response to organic substance | beta-adrenergic receptor kinase activity | import into cell | anatomical structure development | metabolic process | cellular protein localization | amide transport | endocytosis | protein kinase activity | organic substance metabolic process | pigment metabolic process | desensitization of G-protein coupled receptor protein signaling pathway | regulation of phosphate metabolic process | response to alkaloid | establishment of protein localization | multicellular organism aging | regulation of cell communication | negative regulation of signal transduction | signaling | response to organic cyclic compound | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | cellular macromolecule localization | receptor-mediated endocytosis | regulation of G-protein coupled receptor protein signaling pathway | kinase activity | developmental process | cellular protein modification process | receptor metabolic process | response to organonitrogen compound | response to anesthetic | positive regulation of metabolic process | cellular metabolic process | aging | inositol phosphate metabolic process | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
sperm flagellum | supramolecular fiber | dendritic spine | dendrite | intracellular membrane-bounded organelle | sperm midpiece | synapse | neuron projection | somatodendritic compartment | sarcomere | cell | dendrite terminus | myofibril | cytoplasm | intracellular organelle | membrane microdomain | 9+2 motile cilium | motile cilium | dendritic tree | contractile fiber | cell projection | neuron spine | postsynapse | cilium | membrane raft | perinuclear region of cytoplasm | membrane-bounded organelle | dendritic shaft | nucleus | organelle | I band | axon | Z disc | cytosol | intracellular | membrane | supramolecular complex
