QuickView for ATP2C1;jsessionid=E7FD8384BE48DA965CFE20183DB12387;jsessionid=42E05B749B1DB8F2FC6707806049D129;jsessionid=80218235B2FD26AFF3B52B358C4805EC;jsessionid=E43FEB3C70D2123F661E99EE410CC059 (gene)
- Gene Symbol:
- PMR1
Saccharomyces cerevisiae - Full name:
- High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease
- Synonyms:
- BSD1, LDB1, PMR1, pmr1, PMR1, SSC1, YGL167C
- Genomic Location:
- Chr VII: 187622-190474
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GATA3_01 , LYF1_01 , ARP1_01 , ZIC2_01 , CTGCAGY_UNKNOWN , DBP_Q6 , HSF_Q6 , IRF1_Q6 , PAX_Q6 , GGGYGTGNY_UNKNOWN
GO Molecular Function
transition metal ion transmembrane transporter activity | ATPase activity, coupled to transmembrane movement of substances | proton transmembrane transporter activity | cation binding | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | proton-exporting ATPase activity, phosphorylative mechanism | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | manganese ion transmembrane transporter activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | cation transmembrane transporter activity | ATPase activity, coupled | proton-exporting ATPase activity | cation-transporting ATPase activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | manganese-transporting ATPase activity | organic cyclic compound binding | purine ribonucleoside triphosphate binding | calcium-transporting ATPase activity | metal ion transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | calcium ion binding | ATPase coupled ion transmembrane transporter activity | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | monovalent inorganic cation transmembrane transporter activity | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
ATP hydrolysis coupled cation transmembrane transport | transition metal ion transmembrane transporter activity | macroautophagy | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | proton transmembrane transporter activity | cellular chemical homeostasis | cellular process | proton transmembrane transport | localization | cellular homeostasis | metal ion transport | transition metal ion transport | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | catabolic process | transmembrane transporter activity | calcium ion homeostasis | ATP hydrolysis coupled transmembrane transport | proton-exporting ATPase activity, phosphorylative mechanism | divalent metal ion transport | manganese ion transmembrane transporter activity | metal ion homeostasis | calcium ion transmembrane transport | ATP hydrolysis coupled ion transmembrane transport | ion transmembrane transport | cation transmembrane transporter activity | manganese ion transport | proton-exporting ATPase activity | cellular ion homeostasis | cation-transporting ATPase activity | monovalent inorganic cation transport | active transmembrane transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | cellular manganese ion homeostasis | manganese-transporting ATPase activity | cation homeostasis | autophagy | cellular cation homeostasis | cellular calcium ion homeostasis | homeostatic process | cation transmembrane transport | calcium-transporting ATPase activity | metal ion transmembrane transporter activity | metabolic process | chemical homeostasis | calcium ion transport | manganese ion transmembrane transport | ion homeostasis | inorganic cation transmembrane transport | ATPase coupled ion transmembrane transporter activity | transmembrane transport | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | manganese ion homeostasis | cation transport | cellular metal ion homeostasis | ion transport | transition metal ion homeostasis | cellular metabolic process | divalent inorganic cation homeostasis
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | Golgi apparatus | endomembrane system | Golgi membrane | membrane-bounded organelle | organelle | intracellular | membrane
