QuickView for ATP7B;jsessionid=F80952C6C8AD6AA248A37399DA7312F2;jsessionid=6E356E18EFB8C8B8CE29DB6B53DE7704 (gene)
- Gene Symbol:
- Atp7b
Rattus norvegicus - Full name:
- ATPase copper transporting beta
- Synonyms:
- Hts, PINA, Wd, copper-transporting ATPase 2, ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease), PINA gene, promoter, copper pump 2, pineal night-specific ATPase, wilson disease-associated protein homolog
- Genomic Location:
- Chr 16: 74607975-74679349
- Description:
-
plays a role in copper ion transport; partial gene deletion in the Long-Evans Cinnamon (LEC) strain is a model for Wilson disease
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
transition metal ion transmembrane transporter activity | ATPase activity, coupled to transmembrane movement of substances | cation binding | copper-exporting ATPase activity | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | copper-transporting ATPase activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | cation transmembrane transporter activity | ATPase activity, coupled | cation-transporting ATPase activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | copper ion binding | purine ribonucleoside triphosphate binding | zinc ion binding | metal ion transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | transition metal ion binding | ATPase coupled ion transmembrane transporter activity | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | copper ion transmembrane transporter activity | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
ATP hydrolysis coupled cation transmembrane transport | transition metal ion transmembrane transporter activity | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | response to hormone | response to metal ion | cellular chemical homeostasis | intracellular transport | response to organophosphorus | cellular process | secretion | localization | cellular homeostasis | copper-exporting ATPase activity | metal ion transport | transition metal ion transport | copper ion homeostasis | response to inorganic substance | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | establishment of localization in cell | response to peptide hormone | transmembrane transporter activity | calcium ion homeostasis | cellular response to metal ion | response to stimulus | ATP hydrolysis coupled transmembrane transport | response to peptide | circadian rhythm | cellular response to inorganic substance | cellular localization | rhythmic process | metal ion homeostasis | response to nitrogen compound | copper-transporting ATPase activity | system development | zinc ion homeostasis | multicellular organism development | response to purine-containing compound | mammary gland development | ATP hydrolysis coupled ion transmembrane transport | ion transmembrane transport | cation transmembrane transporter activity | cellular ion homeostasis | cation-transporting ATPase activity | response to manganese ion | active transmembrane transporter activity | ion transmembrane transporter activity | cellular copper ion homeostasis | copper ion transmembrane transport | cellular zinc ion homeostasis | cation homeostasis | cellular cation homeostasis | cellular calcium ion homeostasis | homeostatic process | response to zinc ion | intracellular copper ion transport | cation transmembrane transport | response to organic substance | gland development | lactation | metal ion transmembrane transporter activity | anatomical structure development | copper ion import | regulation of body fluid levels | response to prolactin | chemical homeostasis | body fluid secretion | response to copper ion | copper ion export | animal organ development | copper ion transport | ion homeostasis | inorganic cation transmembrane transport | response to cAMP | ATPase coupled ion transmembrane transporter activity | transmembrane transport | inorganic cation transmembrane transporter activity | response to organic cyclic compound | cation transport | developmental process | copper ion transmembrane transporter activity | cellular response to manganese ion | response to organonitrogen compound | cellular metal ion homeostasis | sequestering of calcium ion | ion transport | transition metal ion homeostasis | cellular response to copper ion | divalent inorganic cation homeostasis | multicellular organismal process
GO Cellular Component
trans-Golgi network membrane | occluding junction | integral component of membrane | intracellular membrane-bounded organelle | late endosome | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | apical part of cell | cell-cell junction | Golgi apparatus | endomembrane system | plasma membrane | vesicle | perinuclear region of cytoplasm | Golgi membrane | endosome | membrane-bounded organelle | apical junction complex | organelle | cell periphery | bicellular tight junction | basolateral plasma membrane | trans-Golgi network | intracellular vesicle | intracellular | cell junction | membrane
