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QuickView for AURKB;jsessionid=5DEFB28AA6506D852E208E7810A68700;jsessionid=F0009E9744991C9F42FDD1380CBA9F43;jsessionid=8873197B381133EAF44E61D9DDE3391C (gene)


Gene Symbol:
Aurkb Rattus norvegicus Rattus norvegicus
Full name:
aurora kinase B
Synonyms:
ARK-2, Aim1, STK-1, Stk12, aurora kinase B, AIM-1, aurora 1, aurora- and Ipl1-like midbody-associated protein 1, aurora-B, aurora-related kinase 2, aurora/IPL1-related kinase 2, serine/threonine kinase 12, serine/threonine-protein kinase 12, serine/threonine-protein kinase 5, serine/threonine-protein kinase aurora-B
Genomic Location:
Chr 10: 55798710-55804367
Description:
kinase; involved in proper progression of cytokinesis
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene





GO Molecular Function

kinase binding | cation binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | histone serine kinase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | histone kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of telomere maintenance via telomerase | response to radiation | regulation of cell cycle process | abscission | positive regulation of macromolecule biosynthetic process | negative regulation of cell division | microtubule cytoskeleton organization involved in mitosis | positive regulation of cellular component organization | positive regulation of telomere capping | regulation of programmed cell death | peptidyl-amino acid modification | negative regulation of cellular process | negative regulation of RNA biosynthetic process | histone modification | microtubule cytoskeleton organization | regulation of organelle organization | membrane organization | microtubule-based process | positive regulation of cellular biosynthetic process | cellular process | localization | chromatin organization | cytokinetic process | protein localization to kinetochore | cytoskeleton-dependent cytokinesis | positive regulation of telomerase activity | negative regulation of nucleic acid-templated transcription | macromolecule localization | negative regulation of apoptotic process | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | spindle midzone assembly | spindle assembly | negative regulation of cellular metabolic process | regulation of binding | positive regulation of cytokinesis | regulation of lymphocyte apoptotic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of G2/M transition of mitotic cell cycle | cellular component organization | negative regulation of cytokinesis | regulation of cell division | response to UV | regulation of telomere capping | response to stimulus | regulation of mitotic cell cycle phase transition | chromosome segregation | mitotic spindle organization | cellular response to light stimulus | negative regulation of G2/M transition of mitotic cell cycle | regulation of cell cycle phase transition | protein serine/threonine kinase activity | cellular localization | negative regulation of metabolic process | cellular component assembly | protein modification process | macromolecule modification | positive regulation of telomere maintenance via telomere lengthening | regulation of nucleic acid-templated transcription | organelle assembly | regulation of cell cycle G2/M phase transition | response to light stimulus | cleavage furrow formation | nitrogen compound metabolic process | negative regulation of mitotic cell cycle phase transition | positive regulation of organelle organization | multicellular organism development | negative regulation of cell cycle G2/M phase transition | sister chromatid segregation | phosphorus metabolic process | regulation of telomere maintenance | regulation of catalytic activity | positive regulation of chromosome organization | positive regulation of cell cycle | regulation of gene expression | cell cycle | positive regulation of cellular metabolic process | regulation of telomerase activity | cellular response to radiation | mitotic cytokinesis checkpoint | negative regulation of lymphocyte apoptotic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | protein localization to organelle | negative regulation of binding | histone serine kinase activity | cell proliferation | cell division | negative regulation of B cell apoptotic process | cytokinesis | phosphorylation | positive regulation of telomere maintenance via telomerase | protein phosphorylation | phosphate-containing compound metabolic process | cellular response to UV | regulation of B cell apoptotic process | nuclear chromosome segregation | regulation of telomere maintenance via telomere lengthening | negative regulation of protein binding | regulation of cellular metabolic process | regulation of cytokinesis | positive regulation of DNA biosynthetic process | regulation of RNA metabolic process | histone phosphorylation | regulation of mitotic cell cycle | positive regulation of molecular function | protein metabolic process | histone kinase activity | protein localization to chromosome, centromeric region | anatomical structure development | mitotic cell cycle | nuclear division | metabolic process | histone H3-S28 phosphorylation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | negative regulation of mitotic cell cycle | cellular protein localization | histone-serine phosphorylation | membrane invagination | protein kinase activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | cytoskeleton organization | regulation of chromosome organization | mitotic nuclear division | negative regulation of cell cycle | spindle elongation | negative regulation of molecular function | covalent chromatin modification | regulation of transcription, DNA-templated | regulation of protein binding | protein localization | negative regulation of leukocyte apoptotic process | cellular protein metabolic process | cellular macromolecule localization | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | kinase activity | developmental process | organelle organization | regulation of DNA biosynthetic process | positive regulation of cell cycle process | peptidyl-serine phosphorylation | cellular protein modification process | negative regulation of transcription by RNA polymerase II | mitotic spindle assembly | positive regulation of metabolic process | chromosome organization | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | regulation of cell death | cell cycle checkpoint | negative regulation of cell death | aging | spindle organization | mitotic spindle midzone assembly | mitotic sister chromatid segregation | regulation of cellular component organization | mitotic spindle elongation | protein localization to chromosome | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

condensed nuclear chromosome | mitotic spindle midzone | supramolecular fiber | chromosome | intracellular membrane-bounded organelle | microtubule associated complex | microtubule organizing center | chromosome, centromeric region | condensed chromosome, centromeric region | cell | nuclear lumen | kinetochore | spindle pole centrosome | microtubule | cytoplasm | chromosome passenger complex | spindle | intracellular organelle | centrosome | chromocenter | protein-containing complex | nucleoplasm | midbody | condensed nuclear chromosome, centromeric region | nuclear chromosome | microtubule cytoskeleton | spindle pole | spindle microtubule | spindle midzone | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoskeleton | intracellular | mitotic spindle | supramolecular complex | condensed chromosome