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QuickView for Aldh1a2;jsessionid=C7126EF485AA0938E236E077551770E4;jsessionid=90AB7470F3439B7F451A155D7C54CFC1 (gene)


Gene Symbol:
Aldh1a2 Rattus norvegicus Rattus norvegicus
Full name:
aldehyde dehydrogenase 1 family, member A2
Synonyms:
Raldh-2, retinal dehydrogenase 2, RALDH 2, RalDH(II), aldehyde dehydrogenase 1A2, aldehyde dehydrogenase family 1 member A2, aldehyde dehydrogenase family 1, subfamily A2, ralDH2, retinal dehydrogenase, type II, retinaldehyde-specific dehydrogenase type 2
Genomic Location:
Chr 8: 75681339-75771149
Description:
enzyme necessary for the production of retinoic acid; may be associated with congenital diaphragmatic hernia
Orthologs:
Homo sapiens Mus musculus Saccharomyces cerevisiae Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_053896
Protein Names
Q4FZY8
Q63639



GO Molecular Function

isoprenoid binding | retinoid binding | lipid binding | vitamin binding | catalytic activity | retinal dehydrogenase activity | aldehyde dehydrogenase (NAD) activity | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | oxidoreductase activity | 3-chloroallyl aldehyde dehydrogenase activity | small molecule binding | retinal binding

GO Biological Process

response to extracellular stimulus | brain development | limb development | response to nutrient levels | response to cytokine | muscle tissue development | positive regulation of apoptotic process | morphogenesis of an epithelium | isoprenoid biosynthetic process | regulation of programmed cell death | eye development | response to hormone | negative regulation of cellular process | embryonic appendage morphogenesis | cell differentiation | respiratory tube development | nervous system development | neurogenesis | generation of neurons | mesenchyme development | retinoic acid receptor signaling pathway | pattern specification process | cellular process | limb morphogenesis | heart morphogenesis | response to estradiol | terpenoid biosynthetic process | diencephalon development | tissue development | cellular response to retinoic acid | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | pituitary gland development | retinoic acid biosynthetic process | hepaticobiliary system development | epithelium development | cellular lipid metabolic process | urogenital system development | head development | response to stimulus | vasculature development | mesenchymal cell development | monocarboxylic acid metabolic process | embryonic limb morphogenesis | midgut development | respiratory system development | alcohol metabolic process | regulation of cell proliferation | cardiac muscle tissue development | cardiovascular system development | retinoic acid receptor signaling pathway involved in somitogenesis | retinol metabolic process | cellular biosynthetic process | kidney development | embryo development | blood vessel development | anterior/posterior pattern specification | organic hydroxy compound metabolic process | retinoid metabolic process | system development | multicellular organism development | lipid metabolic process | regulation of hormone levels | embryonic digestive tract development | determination of bilateral symmetry | regulation of gene expression | forelimb morphogenesis | pancreas development | response to lipid | 9-cis-retinoic acid biosynthetic process | animal organ morphogenesis | liver development | embryonic forelimb morphogenesis | small molecule metabolic process | response to nutrient | stem cell differentiation | embryonic camera-type eye development | biosynthetic process | neural tube development | ureter maturation | hindbrain development | digestive tract development | response to vitamin A | lipid biosynthetic process | endocrine system development | sensory organ development | proximal/distal pattern formation | chordate embryonic development | striated muscle tissue development | cell communication | retinoic acid metabolic process | heart development | positive regulation of cell proliferation | embryo development ending in birth or egg hatching | renal system development | response to retinoic acid | retinal metabolic process | embryonic morphogenesis | drug metabolic process | carboxylic acid metabolic process | cellular aldehyde metabolic process | neuron differentiation | regionalization | response to organic substance | gland development | tissue morphogenesis | digestive system development | retinal dehydrogenase activity | aldehyde dehydrogenase (NAD) activity | anatomical structure development | metabolic process | mesenchymal cell differentiation | developmental maturation | oxidation-reduction process | embryonic organ development | 9-cis-retinoic acid metabolic process | positive regulation of cell death | morphogenesis of embryonic epithelium | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | organic substance metabolic process | response to vitamin | animal organ development | regulation of endothelial cell proliferation | forebrain development | positive regulation of programmed cell death | diterpenoid metabolic process | lung development | intracellular receptor signaling pathway | stem cell development | camera-type eye development | anatomical structure formation involved in morphogenesis | signaling | somite development | response to organic cyclic compound | cell development | regulation of epithelial cell proliferation | organic acid metabolic process | hormone metabolic process | anatomical structure morphogenesis | isoprenoid metabolic process | segmentation | developmental process | ureter development | tube development | negative regulation of cell proliferation | neural crest cell differentiation | somitogenesis | central nervous system development | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of cell death | oxidoreductase activity | circulatory system development | neural crest cell development | 3-chloroallyl aldehyde dehydrogenase activity | signal transduction | positive regulation of gene expression | multicellular organismal process | face development

GO Cellular Component

cell | cytoplasm | perinuclear region of cytoplasm | cytosol | intracellular