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QuickView for Atg7;jsessionid=EF2D760DC7DFBAAE18A5DCDCB35AA205;jsessionid=CC24E1315EF8D4FA7FCFAFAB92466134 (gene)


Gene Symbol:
Atg7 Rattus norvegicus Rattus norvegicus
Full name:
autophagy related 7
Synonyms:
Apg7l, ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, ATG7 autophagy related 7 homolog, autophagy 7-like, autophagy related 7 homolog, autophagy-related protein 7, ubiquitin-activating enzyme E1-like protein
Genomic Location:
Chr 4: 150814706-150992704
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Gallus gallus Canis lupus familiaris Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene


Protein Names
Q641Y5



GO Molecular Function

Atg12 activating enzyme activity | catalytic activity | identical protein binding | ubiquitin-like modifier activating enzyme activity | Atg8 activating enzyme activity | protein binding | protein homodimerization activity | transcription factor binding | protein dimerization activity | ligase activity | transferase activity

GO Biological Process

response to extracellular stimulus | brain development | cellular response to increased oxygen levels | positive regulation of insulin secretion involved in cellular response to glucose stimulus | cell morphogenesis | response to virus | response to nutrient levels | regulation of cellular response to oxidative stress | regulation of response to oxidative stress | positive regulation of mucus secretion | neuron projection morphogenesis | regulation of cellular localization | muscle tissue development | positive regulation of apoptotic process | regulation of cell development | regulation of localization | response to isoquinoline alkaloid | macroautophagy | regulation of programmed cell death | negative regulation of cellular response to oxidative stress | negative regulation of phagocytosis | defense response to other organism | establishment of localization | regulation of autophagy | regulation of immune system process | cellular response to hyperoxia | negative regulation of neuron death | negative regulation of cellular process | cell differentiation | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | striated muscle cell development | defense response | nervous system development | cellular response to extracellular stimulus | negative regulation of mitochondrion organization | positive regulation of protein catabolic process | response to drug | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | regulation of DNA replication | regulation of organelle organization | regulation of peptide hormone secretion | generation of neurons | positive regulation of protein secretion | cardiac cell development | membrane organization | negative regulation of DNA metabolic process | autophagy of mitochondrion | regulation of neuron death | cellular process | organic substance catabolic process | response to morphine | negative regulation of oxidative stress-induced neuron death | central nervous system neuron axonogenesis | localization | cellular homeostasis | cell projection morphogenesis | protein transport | neuron development | walking behavior | central nervous system neuron differentiation | anion homeostasis | macromolecule localization | regulation of histone modification | negative regulation of apoptotic process | negative regulation of lipid biosynthetic process | cellular response to starvation | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | forebrain neuron differentiation | negative regulation of peptidyl-lysine acetylation | response to inorganic substance | negative regulation of mitochondrial DNA metabolic process | negative regulation of mitochondrial DNA replication | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | interspecies interaction between organisms | muscle structure development | muscle cell differentiation | protein lipidation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | hepaticobiliary system development | positive regulation of cellular protein metabolic process | negative regulation of oxidative stress-induced cell death | cellular response to organonitrogen compound | negative stranded viral RNA replication | cellular component organization | regulation of histone H4-K16 acetylation | viral life cycle | head development | negative regulation of DNA replication | positive regulation of cellular protein catabolic process | regulation of peptide secretion | lysosomal microautophagy | response to stimulus | muscle cell development | cell morphogenesis involved in neuron differentiation | modulation by virus of host process | metencephalon development | regulation of insulin secretion | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | cellular response to xenobiotic stimulus | response to stress | regulation of protein ubiquitination | cardiac muscle tissue development | response to glucose | response to starvation | positive regulation of proteolysis involved in cellular protein catabolic process | lipoprotein biosynthetic process | positive regulation of proteolysis | positive regulation of hormone secretion | negative regulation of transport | cellular response to organic cyclic compound | regulation of phagocytosis | regulation of protein transport | negative regulation of metabolic process | cellular component assembly | protein modification process | regulation of mucus secretion | regulation of peptide transport | cellular biosynthetic process | mitochondrion organization | macromolecule modification | negative regulation of histone H4 acetylation | pyramidal neuron development | positive regulation of peptide secretion | regulation of cellular response to stress | response to nitrogen compound | central nervous system neuron development | organelle assembly | negative regulation of sphingolipid biosynthetic process | response to external biotic stimulus | system development | cellular response to nutrient levels | response to oxygen levels | nitrogen compound metabolic process | autophagosome organization | multicellular organism development | cerebellum development | regulation of insulin secretion involved in cellular response to glucose stimulus | cellular response to oxidative stress | forebrain neuron development | regulation of hormone levels | regulation of hormone secretion | cellular response to ammonium ion | telencephalon development | axon development | positive regulation of secretion | organic substance transport | cellular response to stress | nervous system process | protein catabolic process | adult walking behavior | regulation of histone H4 acetylation | viral genome replication | modification of morphology or physiology of other organism | positive regulation of cellular metabolic process | defense response to virus | adult locomotory behavior | response to ammonium ion | liver development | cellular response to oxygen levels | suppression by virus of host autophagy | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | peptide transport | cardiocyte differentiation | cellular response to alkaloid | response to oxidative stress | axonogenesis | biosynthetic process | locomotory behavior | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | cardiac muscle cell development | hindbrain development | response to hyperoxia | regulation of DNA-dependent DNA replication | response to xenobiotic stimulus | cell morphogenesis involved in differentiation | post-embryonic development | vacuole organization | autophagy | negative regulation of autophagy | cellular response to drug | regulation of mitochondrion organization | striated muscle tissue development | cell communication | regulation of cellular metabolic process | lipoprotein metabolic process | regulation of protein metabolic process | pyramidal neuron differentiation | heart development | homeostatic process | response to monosaccharide | positive regulation of establishment of protein localization | cellular sphingolipid homeostasis | positive regulation of transport | viral process | positive regulation of peptide hormone secretion | cerebral cortex development | regulation of lipid biosynthetic process | striated muscle cell differentiation | late nucleophagy | organelle disassembly | regulation of proteasomal ubiquitin-dependent protein catabolic process | neuron differentiation | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | gland development | positive regulation of insulin secretion | autophagosome assembly | negative regulation of DNA-dependent DNA replication | regulation of hemopoiesis | anatomical structure development | piecemeal microautophagy of the nucleus | negative regulation of endocytosis | negative regulation of lipid metabolic process | cell projection organization | metabolic process | negative regulation of response to oxidative stress | cellular response to nitrogen starvation | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of body fluid levels | negative regulation of histone H4-K16 acetylation | negative regulation of programmed cell death | regulation of proteasomal protein catabolic process | cellular response to isoquinoline alkaloid | negative regulation of histone acetylation | cerebellar cortex development | amide transport | regulation of vesicle-mediated transport | chemical homeostasis | forebrain generation of neurons | regulation of secretion | behavior | positive regulation of cell death | cellular response to reactive oxygen species | neuron projection development | organic substance metabolic process | cerebellar Purkinje cell layer development | negative regulation of biosynthetic process | animal organ development | response to reactive oxygen species | forebrain development | pallium development | negative regulation of cellular protein metabolic process | regulation of protein secretion | positive regulation of programmed cell death | autophagy of host cells involved in interaction with symbiont | ion homeostasis | protein modification by small protein conjugation or removal | regulation of chromosome organization | response to alkaloid | C-terminal protein lipidation | positive regulation of autophagy | establishment of protein localization | regulation of mitochondrial DNA metabolic process | positive regulation of protein transport | regulation of sphingolipid biosynthetic process | adult behavior | negative regulation of protein metabolic process | organonitrogen compound catabolic process | cardiac muscle cell differentiation | regulation of cell communication | negative regulation of chromosome organization | amino acid homeostasis | response to organic cyclic compound | cell development | regulation of endocytosis | protein localization | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | response to biotic stimulus | regulation of developmental process | developmental process | organelle organization | cellular protein modification process | regulation of histone acetylation | regulation of transport | modulation by virus of host morphology or physiology | negative regulation of protein acetylation | response to organonitrogen compound | central nervous system development | response to anesthetic | cellular response to morphine | regulation of lipid metabolic process | positive regulation of metabolic process | immune system process | response to fluoride | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | response to carbohydrate | negative regulation of cell death | circulatory system development | aging | regulation of ubiquitin-dependent protein catabolic process | lipid homeostasis | regulation of cellular component organization | response to other organism | positive regulation of signaling | regulation of signaling | viral RNA genome replication | post-translational protein modification | macromolecule metabolic process | multicellular organismal process | regulation of chromatin organization

GO Cellular Component

neuron projection | cell | cytoplasm | intracellular organelle | phagophore assembly site | cell projection | plasma membrane bounded cell projection cytoplasm | cilium | cytoplasmic region | axoneme | organelle | ciliary plasm | axon | cytoskeleton | intracellular