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QuickView for BMPR1A;jsessionid=17BE71DB8BDB17168BF082AE0006E776;jsessionid=73902A99610BCABAEE5EB15949CD2CC1;jsessionid=CB4E38979BAECD88E64F2A194EACFE8C (gene)


Gene Symbol:
Bmpr1a Mus musculus Mus musculus
Full name:
bone morphogenetic protein receptor, type 1A
Synonyms:
1110037I22Rik, ALK3, AU045487, BMPR-IA, Bmpr, bone morphogenetic protein receptor type-1A, ALK-3, BMP type-1A receptor, BMP-2/BMP-4 receptor, BMPR-1A, SKR5, activin receptor-like kinase 3, serine/threonine-protein kinase receptor R5
Genomic Location:
Chr 14: 35224254-35315732
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Bos taurus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Protein Names
Q53Z43
P36895



GO Molecular Function

RNA polymerase II transcription factor activity, sequence-specific DNA binding | transforming growth factor beta-activated receptor activity | cation binding | transmembrane signaling receptor activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | transforming growth factor beta receptor activity, type I | growth factor binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | DNA-binding transcription factor activity | transmembrane receptor protein serine/threonine kinase activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | BMP receptor activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | SMAD binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of smooth muscle cell proliferation | brain development | limb development | ventricular cardiac muscle tissue morphogenesis | positive regulation of macromolecule biosynthetic process | pharyngeal system development | regulation of neurogenesis | developmental process involved in reproduction | muscle tissue development | regulation of cell development | regulation of localization | heart trabecula morphogenesis | positive regulation of striated muscle tissue development | regulation of programmed cell death | regulation of cell aging | paraxial mesoderm morphogenesis | dorsal aorta development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | embryonic appendage morphogenesis | regulation of heart growth | regulation of cardiac muscle cell apoptotic process | cell differentiation | positive regulation of epithelial cell proliferation | respiratory tube development | nervous system development | transforming growth factor beta-activated receptor activity | positive regulation of biomineral tissue development | neurogenesis | positive regulation of phosphate metabolic process | anatomical structure regression | generation of neurons | mesenchyme development | blood vessel morphogenesis | regulation of cardiac muscle cell proliferation | pattern specification process | positive regulation of vascular smooth muscle cell proliferation | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | limb morphogenesis | mesoderm morphogenesis | odontogenesis | heart morphogenesis | negative regulation of smooth muscle cell migration | developmental growth | mesoderm development | regulation of embryonic development | positive regulation of pathway-restricted SMAD protein phosphorylation | stem cell population maintenance | regulation of striated muscle tissue development | dorsal/ventral axis specification | response to growth factor | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | diencephalon development | regulation of bone mineralization | tissue development | regulation of cell differentiation | muscle structure development | hindlimb morphogenesis | negative regulation of cell motility | regulation of cellular process | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | pituitary gland development | trabecula morphogenesis | positive regulation of cellular protein metabolic process | regulation of neural crest cell differentiation | epithelium development | ventricular trabecula myocardium morphogenesis | response to transforming growth factor beta | anatomical structure arrangement | head development | regulation of mesodermal cell fate specification | muscle organ morphogenesis | response to stimulus | cardiac right ventricle morphogenesis | vasculature development | mesenchymal cell development | embryonic limb morphogenesis | respiratory system development | paraxial mesoderm development | paraxial mesoderm structural organization | positive regulation of protein metabolic process | mesoderm formation | regulation of SMAD protein signal transduction | regulation of cell proliferation | roof of mouth development | tube morphogenesis | cardiac muscle tissue development | muscle tissue morphogenesis | regulation of epithelial cell differentiation | regulation of smooth muscle cell migration | protein serine/threonine kinase activity | transforming growth factor beta receptor activity, type I | reproduction | atrioventricular valve morphogenesis | cardiovascular system development | cardiac ventricle morphogenesis | heart formation | positive regulation of RNA biosynthetic process | protein modification process | cartilage development | dorsal/ventral pattern formation | embryo development | macromolecule modification | blood vessel development | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to BMP | ventricular compact myocardium morphogenesis | endocardial cushion development | system development | chondrocyte differentiation | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | phosphorus metabolic process | positive regulation of muscle organ development | regulation of phosphorylation | regulation of ossification | artery development | neural plate pattern specification | regulation of gene expression | regulation of cell fate specification | regulation of neural crest cell fate specification | outflow tract morphogenesis | endocardial cushion morphogenesis | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | cardiac conduction system development | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | lateral mesoderm development | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | stem cell differentiation | positive regulation of cardiac ventricle development | pharyngeal arch artery morphogenesis | positive regulation of cardiac muscle cell proliferation | mitral valve development | regulation of cellular protein metabolic process | positive regulation of SMAD protein signal transduction | positive regulation of ossification | mesenchyme morphogenesis | phosphorylation | positive regulation of pri-miRNA transcription by RNA polymerase II | cardiac septum morphogenesis | endocrine system development | protein phosphorylation | phosphate-containing compound metabolic process | regulation of muscle cell apoptotic process | chordate embryonic development | animal organ formation | striated muscle tissue development | cardiac muscle tissue morphogenesis | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | odontogenesis of dentin-containing tooth | mesendoderm development | regulation of protein metabolic process | positive regulation of signal transduction | heart development | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | regulation of stem cell differentiation | fibrous ring of heart morphogenesis | embryonic morphogenesis | mitral valve morphogenesis | positive regulation of osteoblast differentiation | cellular response to transforming growth factor beta stimulus | tricuspid valve development | positive regulation of organ growth | heart valve development | regulation of mesoderm development | protein metabolic process | DNA-binding transcription factor activity | transmembrane receptor protein serine/threonine kinase activity | regionalization | cardiac ventricle development | axis specification | positive regulation of protein modification process | regulation of growth | response to organic substance | gland development | regulation of cardiac muscle tissue development | tissue morphogenesis | artery morphogenesis | Mullerian duct regression | male sex differentiation | regulation of animal organ morphogenesis | ventricular cardiac muscle tissue development | anatomical structure development | cell surface receptor signaling pathway | aorta development | metabolic process | mesenchymal cell differentiation | regulation of RNA biosynthetic process | embryonic organ development | immune response | protein kinase activity | heart valve morphogenesis | organic substance metabolic process | connective tissue development | maintenance of cell number | animal organ development | regulation of endothelial cell proliferation | forebrain development | negative regulation of cellular component movement | dorsal aorta morphogenesis | regulation of phosphate metabolic process | BMP signaling pathway involved in heart development | positive regulation of muscle tissue development | atrioventricular valve development | ectoderm development | aorta morphogenesis | lung development | stem cell development | transforming growth factor beta receptor signaling pathway | anatomical structure formation involved in morphogenesis | BMP signaling pathway | BMP receptor activity | regulation of cell communication | positive regulation of developmental growth | signaling | somite development | positive regulation of growth | regulation of transcription, DNA-templated | cell development | embryonic digit morphogenesis | regulation of developmental growth | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | endocardial cushion formation | endoderm development | anatomical structure morphogenesis | regulation of organ growth | regulation of nervous system development | neural plate mediolateral regionalization | regulation of developmental process | kinase activity | segmentation | regulation of mesenchymal cell proliferation | developmental process | cardiac septum development | cellular protein modification process | tube development | regulation of gastrulation | positive regulation of transcription, DNA-templated | positive regulation of mesenchymal cell proliferation | regulation of endothelial cell differentiation | positive regulation of nucleic acid-templated transcription | positive regulation of heart growth | neural crest cell differentiation | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | regulation of epithelial to mesenchymal transition | cardiac chamber development | somitogenesis | regulation of neural crest formation | regulation of cell fate commitment | central nervous system development | in utero embryonic development | positive regulation of metabolic process | cellular response to BMP stimulus | skeletal system development | tricuspid valve morphogenesis | gastrulation | immune system process | cellular metabolic process | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cardiac muscle tissue development | regulation of smooth muscle cell proliferation | negative regulation of cell development | circulatory system development | negative regulation of locomotion | neural crest cell development | negative regulation of cell differentiation | regulation of lateral mesodermal cell fate specification | positive regulation of bone mineralization | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | regulation of pathway-restricted SMAD protein phosphorylation | positive regulation of gene expression | outflow tract septum morphogenesis | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | negative regulation of neurogenesis | regulation of cellular senescence | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | intrinsic component of membrane | external side of plasma membrane | receptor complex | membrane microdomain | dendritic tree | protein-containing complex | cell projection | plasma membrane | membrane raft | integral component of plasma membrane | cell periphery | plasma membrane raft | cell surface | caveola | membrane | intrinsic component of plasma membrane