QuickView for BRG1;jsessionid=47B257CB53843B6B0211E8A1FACD0394;jsessionid=6A69F0F623504CAA16E29BA2F7E9D22C (gene)
- Gene Symbol:
- Smarca4
Rattus norvegicus - Full name:
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
- Synonyms:
- brg-1, transcription activator BRG1, ATP-dependent helicase SMARCA4, BAF190A, BRG1-associated factor 190A, SNF2-beta, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4, protein brahma homolog 1
- Genomic Location:
- Chr 8: 20720965-20812157
- Description:
-
mouse homolog is a catalytic subunit of mammalian chromatin-remodeling complexes
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Gallus gallus , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | core promoter binding | hormone receptor binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | protein-containing complex binding | ribonucleotide binding | DNA polymerase binding | nucleotide binding | signaling receptor binding | hydrolase activity | carbohydrate derivative binding | RNA polymerase I regulatory region sequence-specific DNA binding | lysine-acetylated histone binding | ATPase activity | pyrophosphatase activity | catalytic activity | chromatin binding | ATP binding | protein N-terminus binding | anion binding | adenyl nucleotide binding | modification-dependent protein binding | nucleoside-triphosphatase activity | RNA polymerase II regulatory region DNA binding | p53 binding | androgen receptor binding | ATPase activity, coupled | RNA polymerase I regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | purine nucleotide binding | transcription corepressor activity | nuclear hormone receptor binding | ion binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | purine ribonucleoside triphosphate binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcription factor binding | hydrolase activity, acting on acid anhydrides | RNA polymerase II regulatory region sequence-specific DNA binding | histone binding | core promoter sequence-specific DNA binding | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | steroid hormone receptor binding | helicase activity | drug binding | transcription coregulator activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | Tat protein binding | RNA polymerase I CORE element sequence-specific DNA binding | small molecule binding | RNA binding
GO Biological Process
RNA metabolic process | brain development | limb development | DNA-templated transcription, initiation | cell morphogenesis | positive regulation of macromolecule biosynthetic process | epidermis morphogenesis | extracellular structure organization | pharyngeal system development | developmental process involved in reproduction | regulation of localization | heart trabecula morphogenesis | morphogenesis of an epithelium | positive regulation of DNA-binding transcription factor activity | nucleosome organization | regulation of programmed cell death | peptidyl-amino acid modification | erythrocyte homeostasis | eye development | regulation of transcription by RNA polymerase I | smooth muscle cell differentiation | myeloid cell differentiation | DNA modification | transcription initiation from RNA polymerase I promoter | hatching | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | embryonic appendage morphogenesis | histone modification | cell differentiation | aortic smooth muscle cell differentiation | male gamete generation | nervous system development | histone H3 acetylation | neurogenesis | interaction with symbiont | blood vessel morphogenesis | neural retina development | positive regulation of cellular biosynthetic process | cellular process | regulation of gene expression, epigenetic | regulation of cell motility | chromatin organization | limb morphogenesis | protein-DNA complex disassembly | heart morphogenesis | negative regulation of signaling | developmental growth | immune system development | multicellular organismal reproductive process | negative regulation of nucleic acid-templated transcription | stem cell population maintenance | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of cell differentiation | gamete generation | interspecies interaction between organisms | muscle structure development | muscle cell differentiation | hindlimb morphogenesis | regulation of cellular process | regulation of apoptotic process | gene silencing | regulation of metabolic process | gliogenesis | positive regulation by host of viral transcription | hepaticobiliary system development | organic cyclic compound metabolic process | trabecula morphogenesis | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | head development | vasculature development | embryonic limb morphogenesis | regulation of intracellular steroid hormone receptor signaling pathway | transcription by RNA polymerase I | germ cell development | cellular nitrogen compound biosynthetic process | heart trabecula formation | regulation of cell proliferation | vascular smooth muscle cell differentiation | tube morphogenesis | epithelial cell development | protein-DNA complex assembly | reproduction | cardiovascular system development | peptidyl-lysine acetylation | cellular nitrogen compound metabolic process | extracellular matrix organization | regulation of DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | spermatid differentiation | hemopoiesis | cellular component assembly | protein modification process | cellular biosynthetic process | embryo development | macromolecule modification | blood vessel development | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | nucleosome disassembly | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of growth | positive regulation of viral process | multicellular organism development | protein acetylation | artery development | ATP-dependent chromatin remodeling | regulation of gene expression | methylation | outflow tract morphogenesis | modification of morphology or physiology of other organism | coronary vasculature development | blastocyst hatching | negative regulation of gene expression, epigenetic | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | liver development | regulation of nitrogen compound metabolic process | definitive hemopoiesis | regulation of cell migration | transcription corepressor activity | regulation of cellular component movement | regulation of transcription by RNA polymerase II | DNA methylation | DNA methylation on cytosine | positive regulation of cell differentiation | epidermal cell differentiation | homeostasis of number of cells | negative regulation of intracellular steroid hormone receptor signaling pathway | histone acetylation | internal peptidyl-lysine acetylation | pharyngeal arch artery morphogenesis | biosynthetic process | aromatic compound biosynthetic process | glial cell differentiation | hindbrain development | positive regulation of pri-miRNA transcription by RNA polymerase II | cellular protein-containing complex assembly | epidermis development | DNA-templated transcriptional preinitiation complex assembly | skin development | keratinocyte differentiation | sensory organ development | chordate embryonic development | regulation of cellular metabolic process | chromatin remodeling | positive regulation of transcription of nucleolar large rRNA by RNA polymerase I | positive regulation of signal transduction | vasculogenesis | regulation of androgen receptor signaling pathway | heart development | glial cell fate determination | homeostatic process | DNA methylation on cytosine within a CG sequence | positive regulation of cell proliferation | regulation of locomotion | embryo development ending in birth or egg hatching | transcription coactivator activity | regulation of RNA metabolic process | negative regulation of cell growth | regulation of viral process | embryonic hindlimb morphogenesis | embryonic morphogenesis | regulation of glucose mediated signaling pathway | positive regulation of molecular function | multicellular organism reproduction | embryonic organ morphogenesis | protein-containing complex assembly | ventricular septum development | protein metabolic process | cardiac ventricle development | regulation of growth | gland development | tissue morphogenesis | artery morphogenesis | positive regulation of glucose mediated signaling pathway | retina development in camera-type eye | DNA metabolic process | positive regulation of viral transcription | regulation of DNA-binding transcription factor activity | chromatin assembly or disassembly | anatomical structure development | aorta development | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | RNA polymerase I transcriptional preinitiation complex assembly | negative regulation of programmed cell death | embryonic organ development | lens fiber cell development | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | maintenance of cell number | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | gene expression | definitive erythrocyte differentiation | positive regulation of transcription by RNA polymerase I | regulation of Wnt signaling pathway | spermatid development | positive regulation of binding | transcription, DNA-templated | blastocyst development | camera-type eye development | modulation by host of viral transcription | anatomical structure formation involved in morphogenesis | methylation-dependent chromatin silencing | negative regulation of androgen receptor signaling pathway | regulation of cell communication | negative regulation of signal transduction | covalent chromatin modification | regulation of transcription, DNA-templated | glial cell fate commitment | cell development | positive regulation of DNA binding | internal protein amino acid acetylation | protein-containing complex disassembly | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | organelle organization | erythrocyte differentiation | regulation of cell growth | spermatogenesis | cardiac septum development | blastocyst growth | cellular protein modification process | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | cell fate determination | transcription coregulator activity | epithelial cell differentiation | positive regulation of transcription by RNA polymerase II | cardiac chamber development | heterocycle metabolic process | central nervous system development | in utero embryonic development | regulation of viral transcription | positive regulation of metabolic process | chromosome organization | chromatin silencing | immune system process | positive regulation of Wnt signaling pathway | cellular metabolic process | hematopoietic or lymphoid organ development | regulation of cell death | lens fiber cell differentiation | negative regulation of cell death | circulatory system development | sexual reproduction | regulation of cellular component organization | lens development in camera-type eye | RNA polymerase I CORE element sequence-specific DNA binding | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
nuclear euchromatin | chromosome | intracellular membrane-bounded organelle | catalytic complex | perichromatin fibrils | cell | nuclear lumen | nucleolus | intracellular organelle | euchromatin | protein-containing complex | chromatin | nuclear chromosome | npBAF complex | membrane-bounded organelle | heterochromatin | nucleus | organelle | SWI/SNF superfamily-type complex | nBAF complex | membrane-enclosed lumen | nuclear chromatin | ATPase complex | SWI/SNF complex | intracellular
