QuickView for Bcl1;jsessionid=B439931287425E0BC6A47A9F8F4C0B87;jsessionid=513AB9E11AC6C3F9FF5C28632ADF38CB (gene)
- Gene Symbol:
- Ccnd1
Rattus norvegicus - Full name:
- cyclin D1
- Synonyms:
- G1/S-specific cyclin-D1
- Genomic Location:
- Chr 1: 205357283-205366751
- Description:
-
regulatory subunit of CDK4 or CDK6; involved in regulation of the G1/S transition of the cell cycle
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-1 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-323 , Predicted Gene Targets for miR-338 , Predicted Gene Targets for miR-34 , Predicted Gene Targets for miR-503 , Predicted Gene Targets for miR-93
GO Molecular Function
kinase binding | protein kinase regulator activity | kinase regulator activity | protein kinase binding | enzyme binding | protein-containing complex binding | cyclin-dependent protein kinase activity | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | proline-rich region binding | transcription corepressor activity | protein binding | transcription factor binding | cyclin-dependent protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | enzyme regulator activity | kinase activity | histone deacetylase binding | transcription coregulator activity | cyclin-dependent protein serine/threonine kinase regulator activity
GO Biological Process
positive regulation of cyclin-dependent protein serine/threonine kinase activity | RNA metabolic process | response to extracellular stimulus | response to radiation | regulation of cell cycle process | response to nutrient levels | response to endoplasmic reticulum stress | developmental process involved in reproduction | regulation of cell cycle G1/S phase transition | protein kinase regulator activity | gonad development | positive regulation of G1/S transition of mitotic cell cycle | response to X-ray | establishment of localization | response to hormone | positive regulation of G2/M transition of mitotic cell cycle | negative regulation of cellular process | positive regulation of developmental process | negative regulation of RNA biosynthetic process | response to metal ion | cell differentiation | positive regulation of epithelial cell proliferation | response to drug | regulation of G1/S transition of mitotic cell cycle | positive regulation of phosphate metabolic process | regulation of organelle organization | response to antibiotic | cellular process | secretion | Leydig cell differentiation | response to magnesium ion | localization | mitotic DNA integrity checkpoint | negative regulation of signaling | negative regulation of G1/S transition of mitotic cell cycle | kinase regulator activity | reproductive system development | canonical Wnt signaling pathway | response to estradiol | regulation of mitotic nuclear division | negative regulation of nucleic acid-templated transcription | positive regulation of protein kinase activity | endoplasmic reticulum unfolded protein response | response to corticosterone | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell cycle arrest | response to inorganic substance | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | regeneration | regulation of cellular process | regulation of metabolic process | hepaticobiliary system development | positive regulation of cyclin-dependent protein kinase activity | positive regulation of cell cycle phase transition | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | cellular response to unfolded protein | response to topologically incorrect protein | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | cellular response to topologically incorrect protein | development of primary sexual characteristics | response to UV | response to stimulus | cyclin-dependent protein kinase activity | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | regulation of mammary gland epithelial cell proliferation | regulation of cell cycle phase transition | regulation of epithelial cell differentiation | protein serine/threonine kinase activity | positive regulation of mammary gland epithelial cell proliferation | reproduction | response to alcohol | cellular nitrogen compound metabolic process | cell cycle G1/S phase transition | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | protein modification process | cellular biosynthetic process | response to iron ion | macromolecule modification | cell-cell signaling | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | response to ethanol | regulation of nucleic acid-templated transcription | response to nitrogen compound | regulation of cell cycle G2/M phase transition | response to light stimulus | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | Wnt signaling pathway | mitotic DNA damage checkpoint | multicellular organism development | response to UV-A | phosphorus metabolic process | mammary gland development | response to vitamin E | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | positive regulation of cell cycle | mammary gland lobule development | positive regulation of mitotic cell cycle | regulation of gene expression | response to ketone | cellular response to stress | response to lipid | cell cycle | regulation of cell cycle arrest | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | liver development | regulation of nitrogen compound metabolic process | response to corticosteroid | transcription corepressor activity | regulation of transcription by RNA polymerase II | response to nutrient | positive regulation of cell cycle G2/M phase transition | fat cell differentiation | cell proliferation | biosynthetic process | cell division | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | mammary gland epithelial cell proliferation | response to toxic substance | mitotic cell cycle phase transition | positive regulation of cell cycle G1/S phase transition | protein phosphorylation | phosphate-containing compound metabolic process | mitotic G1 DNA damage checkpoint | response to estrogen | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | liver regeneration | regulation of protein metabolic process | G1/S transition of mitotic cell cycle | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | regulation of mitotic cell cycle | negative regulation of epithelial cell differentiation | positive regulation of molecular function | development of primary male sexual characteristics | protein metabolic process | positive regulation of protein modification process | response to organic substance | gland development | G1 DNA damage checkpoint | epithelial cell proliferation | lactation | regulation of kinase activity | male sex differentiation | cyclin-dependent protein serine/threonine kinase activity | response to leptin | anatomical structure development | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | cell surface receptor signaling pathway | metabolic process | response to mineralocorticoid | regulation of RNA biosynthetic process | regulation of body fluid levels | negative regulation of transcription, DNA-templated | male gonad development | negative regulation of mitotic cell cycle | body fluid secretion | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | response to vitamin | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | positive regulation of kinase activity | re-entry into mitotic cell cycle | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | mammary gland epithelium development | transcription, DNA-templated | mammary gland alveolus development | negative regulation of cell cycle | regulation of cell communication | negative regulation of cell cycle G1/S phase transition | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | response to unfolded protein | cellular macromolecule biosynthetic process | reproductive structure development | regulation of developmental process | kinase activity | developmental process | positive regulation of cell cycle process | cellular protein modification process | mitotic G1/S transition checkpoint | negative regulation of transcription by RNA polymerase II | response to organonitrogen compound | cell cycle phase transition | transcription coregulator activity | heterocycle metabolic process | response to calcium ion | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | cellular response to organic substance | sex differentiation | response to steroid hormone | DNA damage checkpoint | cell cycle checkpoint | negative regulation of cell differentiation | regulation of cellular component organization | response to ionizing radiation | signal transduction | regulation of signaling | animal organ regeneration | response to glucocorticoid | cyclin-dependent protein serine/threonine kinase regulator activity | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
occluding junction | intracellular membrane-bounded organelle | catalytic complex | protein kinase complex | cell | nuclear lumen | cytoplasm | intracellular organelle | cell-cell junction | protein-containing complex | nucleoplasm | transferase complex | serine/threonine protein kinase complex | membrane-bounded organelle | transcriptional repressor complex | apical junction complex | nucleus | organelle | bicellular tight junction | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | intracellular | cell junction | membrane
