QuickView for C5a;jsessionid=5EF92C9DFB99504F33E7A532681AE529;jsessionid=086A00ED425EA31F980046C26F7BB088;jsessionid=CFE56490507517194937C115098B2C90 (gene)
- Gene Symbol:
- C5
Rattus norvegicus - Full name:
- complement C5
- Synonyms:
- C5a, Hc, RGD1561905, complement C5, anaphylatoxin, complement component 5
- Genomic Location:
- Chr 3: 14011115-14102744
- Description:
-
likely component of the classical pathway of the complement cascade; may be involved with tissue injury associated with ischemia or sepsis; may be a component of the membrane attack complex
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
YY1_01 , BRN2_01 , PAX4_02 , POU6F1_01 , CRX_Q4 , HNF3ALPHA_Q6 , HNF1_Q6 , GCTTGAA_MIR498 , TGACATY_UNKNOWN , TTANTCA_UNKNOWN
| Protein Names |
|---|
| No proteins found. |
GO Molecular Function
endopeptidase inhibitor activity | C5a anaphylatoxin chemotactic receptor binding | enzyme inhibitor activity | signaling receptor binding | molecular function regulator | protein binding | G-protein coupled receptor binding | peptidase inhibitor activity | enzyme regulator activity
GO Biological Process
positive regulation of immune response | regulation of leukocyte chemotaxis | adaptive immune response | positive regulation of locomotion | endopeptidase inhibitor activity | negative regulation of immune system process | cell motility | regulation of localization | complement activation | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | defense response | cellular chemical homeostasis | negative regulation of dopamine secretion | glucose homeostasis | positive regulation of protein secretion | negative regulation of proteolysis | positive regulation of chemokine secretion | cellular process | regulation of catecholamine secretion | regulation of cell motility | localization | cellular homeostasis | regulation of chemotaxis | negative regulation of secretion | regulation of proteolysis | negative regulation of cell migration | negative regulation of macrophage migration | negative regulation of cellular metabolic process | negative regulation of cell motility | regulation of angiogenesis | regulation of immune response | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | negative regulation of chemotaxis | negative regulation of response to drug | calcium ion homeostasis | regulation of peptide secretion | regulation of vasculature development | response to stimulus | enzyme inhibitor activity | positive regulation of immune system process | regulation of norepinephrine secretion | response to stress | regulation of response to drug | positive regulation of vascular endothelial growth factor production | negative regulation of leukocyte chemotaxis | positive regulation of cytokine secretion | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | regulation of peptide transport | embryo development | molecular function regulator | metal ion homeostasis | leukocyte migration | positive regulation of peptide secretion | locomotion | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | nitrogen compound metabolic process | negative regulation of secretion by cell | multicellular organism development | negative regulation of catalytic activity | cell migration | regulation of peptidase activity | leukocyte mediated immunity | regulation of catalytic activity | negative regulation of peptidase activity | positive regulation of chemotaxis | complement activation, alternative pathway | positive regulation of secretion | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cellular component movement | negative regulation of norepinephrine secretion | regulation of cellular protein metabolic process | negative regulation of ion transport | positive regulation of chemokine production | protein activation cascade | cation homeostasis | regulation of leukocyte migration | chordate embryonic development | cellular cation homeostasis | regulation of cellular metabolic process | humoral immune response | inflammatory response | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | positive regulation of establishment of protein localization | regulation of locomotion | embryo development ending in birth or egg hatching | positive regulation of transport | negative regulation of catecholamine secretion | regulation of dopamine secretion | regulation of cytokine secretion | activation of immune response | protein metabolic process | regulation of establishment of protein localization | anatomical structure development | complement activation, classical pathway | metabolic process | chemical homeostasis | regulation of secretion | immune response | organic substance metabolic process | negative regulation of cellular protein metabolic process | negative regulation of cellular component movement | regulation of protein secretion | negative regulation of macrophage chemotaxis | ion homeostasis | positive regulation of cytokine production | positive regulation of protein transport | leukocyte migration involved in inflammatory response | negative regulation of protein metabolic process | humoral immune response mediated by circulating immunoglobulin | negative regulation of molecular function | peptidase inhibitor activity | enzyme regulator activity | regulation of cytokine production | regulation of endopeptidase activity | negative regulation of leukocyte migration | regulation of developmental process | B cell mediated immunity | regulation of ion transport | developmental process | regulation of chemokine production | regulation of transport | innate immune response | cellular metal ion homeostasis | regulation of vascular endothelial growth factor production | negative regulation of hydrolase activity | regulation of macrophage chemotaxis | in utero embryonic development | immunoglobulin mediated immune response | immune system process | regulation of protein localization | carbohydrate homeostasis | chemotaxis | divalent inorganic cation homeostasis | negative regulation of locomotion | positive regulation of angiogenesis | negative regulation of endopeptidase activity | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
integral component of membrane | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | plasma membrane | integral component of plasma membrane | extracellular region | extracellular space | cell periphery | pore complex | membrane attack complex | membrane | intrinsic component of plasma membrane
