QuickView for C8B;jsessionid=764D4E2FCA602C494C14E61C3EEAF907;jsessionid=0DEC83D170F38714683A2D57C88C4BBE (gene)

Gene Symbol:

C8b Mus musculus

Full name:

complement component 8, beta polypeptide

Synonyms:

4930439B20Rik, AI595927, complement component C8 beta chain, complement component 8, beta subunit

Genomic Location:

Chr 4: 104438922-104477153

Description:

This gene encodes the beta subunit of complement component C8 that participates in the assembly of the complement membrane attack complex. The encoded preproprotein undergoes proteolytic processing to generate the beta subunit, which associates with the alpha and gamma subunits to form a trimeric complement component, C8. Alternative splicing resul...

View Full Description

This gene encodes the beta subunit of complement component C8 that participates in the assembly of the complement membrane attack complex. The encoded preproprotein undergoes proteolytic processing to generate the beta subunit, which associates with the alpha and gamma subunits to form a trimeric complement component, C8. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. This gene is located adjacent to the gene encoding the alpha subunit.

View Less

Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF3ALPHA_Q6 ,  HNF3_Q6 ,  TGCTGAY_UNKNOWN ,  WTGAAAT_UNKNOWN

search → result