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QuickView for CACNA1C;jsessionid=13EA0BC64892CE2257EC76714EFB31CB;jsessionid=8087FB1115A63FF41773361232FADC19 (gene)


Gene Symbol:
Cacna1c Rattus norvegicus Rattus norvegicus
Full name:
calcium voltage-gated channel subunit alpha1 C
Synonyms:
RATIVS302, voltage-dependent L-type calcium channel subunit alpha-1C, L-type calcium channel alpha-1 subunit, RBC, brain class C, calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, calcium channel, voltage-dependent, L type, alpha 1C subunit, calcium channel, voltage-dependent, alpha 1C subunit, voltage-gated calcium channel subunit alpha Cav1.2
Genomic Location:
Chr 4: 154895691-155517389
Description:
subunit of an L-type calcium channel that may be involved in bone metabolism and compensatory renal growth
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

translation initiation factor binding | high voltage-gated calcium channel activity | protein phosphatase 2A binding | voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | enzyme binding | transmembrane transporter activity | ion gated channel activity | alpha-actinin binding | ion channel binding | voltage-gated calcium channel activity | voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential | protein domain specific binding | cytoskeletal protein binding | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | protein binding | protein phosphatase binding | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | calmodulin binding | phosphatase binding | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | actinin binding | metal ion binding | ion channel activity | substrate-specific channel activity | voltage-gated calcium channel activity involved in AV node cell action potential

GO Biological Process

limb development | regulation of blood vessel diameter | response to radiation | regulation of muscle system process | heart process | actin filament-based process | exocytosis | regulation of cellular localization | intracellular signal transduction | cytosolic calcium ion transport | regulation of localization | high voltage-gated calcium channel activity | hormone secretion | eye development | establishment of localization | embryonic appendage morphogenesis | membrane depolarization during action potential | cellular chemical homeostasis | glucose homeostasis | voltage-gated ion channel activity | regulation of ventricular cardiac muscle cell action potential | AV node cell to bundle of His cell signaling | membrane depolarization during atrial cardiac muscle cell action potential | calcium ion import | cellular process | secretion | peptide hormone secretion | localization | cellular homeostasis | limb morphogenesis | protein transport | passive transmembrane transporter activity | metal ion transport | visual learning | chemical synaptic transmission | walking behavior | immune system development | learning | macromolecule localization | calcium ion transmembrane transport via high voltage-gated calcium channel | establishment of localization in cell | actin filament-based movement | atrial cardiac muscle cell action potential | regulation of cellular process | membrane depolarization during cardiac muscle cell action potential | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | heart contraction | smooth muscle contraction | actin-mediated cell contraction | calcium ion homeostasis | calcium ion transport into cytosol | muscle contraction | associative learning | response to stimulus | ion gated channel activity | embryonic limb morphogenesis | regulation of blood vessel size | regulation of cardiac muscle contraction by calcium ion signaling | regulation of blood circulation | regulation of cardiac muscle cell contraction | regulation of heart rate | cellular localization | divalent metal ion transport | secretion by cell | blood circulation | embryo development | cell-cell signaling | insulin secretion | metal ion homeostasis | urinary bladder smooth muscle contraction | regulation of membrane potential | voltage-gated calcium channel activity | voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of calcium ion transport into cytosol | response to light stimulus | system development | growth hormone secretion | multicellular organism development | calcium ion transmembrane transport | learning or memory | regulation of muscle contraction | regulation of hormone levels | ion transmembrane transport | forelimb morphogenesis | regulation of postsynaptic membrane potential | organic substance transport | nervous system process | regulation of blood pressure | synaptic signaling | adult walking behavior | cation transmembrane transporter activity | excretion | cellular ion homeostasis | adult locomotory behavior | positive regulation of cytosolic calcium ion concentration | embryonic forelimb morphogenesis | peptide transport | vesicle-mediated transport | regulation of cellular component movement | cardiac muscle cell action potential involved in contraction | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | second-messenger-mediated signaling | cognition | regulation of release of sequestered calcium ion into cytosol | locomotory behavior | regulated exocytosis | regulation of calcium ion transmembrane transport | cell-cell signaling involved in cardiac conduction | regulation of heart contraction | cation homeostasis | sensory organ development | regulation of striated muscle contraction | peptide secretion | cellular cation homeostasis | cell communication | cardiac muscle cell contraction | regulation of cardiac muscle contraction | regulation of cardiac muscle cell action potential | smooth muscle contraction involved in micturition | heart development | cellular calcium ion homeostasis | homeostatic process | regulation of tube size | striated muscle contraction | embryonic morphogenesis | calcium-mediated signaling | cation transmembrane transport | regulation of heart rate by cardiac conduction | regulation of growth | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | visual behavior | atrial cardiac muscle cell to AV node cell communication | metal ion transmembrane transporter activity | anatomical structure development | voltage-gated cation channel activity | regulation of vasoconstriction | AV node cell action potential | AV node cell to bundle of His cell communication | regulation of tube diameter | cell communication involved in cardiac conduction | amide transport | calcium ion regulated exocytosis | chemical homeostasis | calcium ion transport | behavior | membrane depolarization | hormone transport | regulation of sequestering of calcium ion | animal organ development | micturition | ion homeostasis | inorganic cation transmembrane transport | regulation of ion transmembrane transport | renal system process | establishment of protein localization | camera-type eye development | cation channel activity | adult behavior | regulation of action potential | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | regulation of developmental growth | protein localization | voltage-gated channel activity | anatomical structure morphogenesis | cation transport | channel activity | regulation of organ growth | regulation of developmental process | regulation of ion transport | developmental process | calcium channel activity | regulation of calcium ion transport | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | regulation of transport | cardiac muscle cell action potential | signal release | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | cellular metal ion homeostasis | ion channel activity | regulation of actin filament-based process | ion transport | cardiac muscle contraction | immune system process | protein secretion | circulatory system development | carbohydrate homeostasis | divalent inorganic cation homeostasis | substrate-specific channel activity | voltage-gated calcium channel activity involved in AV node cell action potential | muscle system process | signal transduction | cardiac conduction | multicellular organismal process | membrane depolarization during AV node cell action potential

GO Cellular Component

presynaptic membrane | supramolecular fiber | integral component of membrane | dendrite | intracellular membrane-bounded organelle | sarcolemma | synapse | neuron projection | somatodendritic compartment | sarcomere | voltage-gated calcium channel complex | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | myofibril | cytoplasm | intracellular organelle | membrane microdomain | dendritic tree | contractile fiber | presynapse | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane bounded cell projection cytoplasm | plasma membrane | membrane raft | postsynaptic density | asymmetric synapse | cytoplasmic region | integral component of plasma membrane | T-tubule | calcium channel complex | membrane-bounded organelle | dendritic shaft | nucleus | organelle | axon cytoplasm | postsynaptic specialization | I band | cell periphery | L-type voltage-gated calcium channel complex | axon | basolateral plasma membrane | transmembrane transporter complex | neuron projection terminus | plasma membrane raft | cation channel complex | ion channel complex | Z disc | basal pole of outer hair cell | caveolar macromolecular signaling complex | intracellular | caveola | membrane | supramolecular complex | intrinsic component of plasma membrane | cell pole