QuickView for CASP-2;jsessionid=5DEB2FCE89368D47002682B883EC5C23;jsessionid=BFD709773B2C37E861D32D9AA978BE47 (gene)
- Gene Symbol:
- CASP2
Gallus gallus - Full name:
- caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)
- Synonyms:
- ICH-1
- Genomic Location:
- Chr 1: 80809182-80835916
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cysteine-type endopeptidase activity involved in apoptotic process | hydrolase activity | cysteine-type peptidase activity | catalytic activity | protein domain specific binding | cysteine-type endopeptidase activity involved in execution phase of apoptosis | identical protein binding | cysteine-type endopeptidase activity | protein binding | endopeptidase activity | peptidase activity
GO Biological Process
regulation of cell cycle process | developmental process involved in reproduction | intracellular signal transduction | positive regulation of apoptotic process | proteolysis | regulation of cell cycle G1/S phase transition | regulation of programmed cell death | negative regulation of cellular process | protein processing | cell differentiation | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | regulation of G1/S transition of mitotic cell cycle | cellular process | extrinsic apoptotic signaling pathway | mitotic DNA integrity checkpoint | negative regulation of G1/S transition of mitotic cell cycle | cysteine-type endopeptidase activity involved in apoptotic process | regulation of cell cycle | regulation of cellular process | regulation of apoptotic process | signal transduction involved in mitotic DNA damage checkpoint | response to stimulus | cellular response to mechanical stimulus | regulation of mitotic cell cycle phase transition | response to stress | regulation of cell cycle phase transition | execution phase of apoptosis | programmed cell death | reproduction | cysteine-type peptidase activity | apoptotic process | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | cysteine-type endopeptidase activity involved in execution phase of apoptosis | DNA damage response, signal transduction by p53 class mediator | mitotic DNA damage checkpoint | cellular response to DNA damage stimulus | positive regulation of cell cycle | signal transduction in response to DNA damage | cellular response to stress | cell cycle | regulation of cell cycle arrest | protein maturation | regulation of apoptotic signaling pathway | signal transduction involved in cell cycle checkpoint | programmed cell death involved in cell development | mitotic G1 DNA damage checkpoint | cell communication | positive regulation of signal transduction | cysteine-type endopeptidase activity | apoptotic signaling pathway | regulation of mitotic cell cycle | positive regulation of cell cycle arrest | protein metabolic process | G1 DNA damage checkpoint | response to mechanical stimulus | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | metabolic process | negative regulation of mitotic cell cycle | positive regulation of cell death | organic substance metabolic process | cell death | gene expression | positive regulation of programmed cell death | signal transduction involved in mitotic cell cycle checkpoint | negative regulation of cell cycle | regulation of cell communication | negative regulation of cell cycle G1/S phase transition | signaling | endopeptidase activity | cell development | extrinsic apoptotic signaling pathway in absence of ligand | signal transduction involved in DNA damage checkpoint | developmental process | positive regulation of cell cycle process | mitotic G1/S transition checkpoint | signal transduction involved in mitotic G1 DNA damage checkpoint | mitotic cell cycle checkpoint | negative regulation of cell cycle process | peptidase activity | regulation of cell death | ectopic germ cell programmed cell death | DNA damage checkpoint | cell cycle checkpoint | signal transduction by p53 class mediator | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
