QuickView for CASP8;jsessionid=4E40A9D03E0238782C6E1853C45E3CC1;jsessionid=3509C4BAFE73FF02172A4F4339D00AE2;jsessionid=8F93CB5E9C73C3D7A1302DF23FCA2164 (gene)
- Gene Symbol:
- CASP8
Bos taurus - Full name:
- caspase 8, apoptosis-related cysteine peptidase
- Synonyms:
- N/A
- Genomic Location:
- Chr 2: 94153163-94176829
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cysteine-type endopeptidase activity involved in apoptotic signaling pathway | cysteine-type endopeptidase activity involved in apoptotic process | enzyme binding | hydrolase activity | cysteine-type peptidase activity | catalytic activity | protein domain specific binding | ubiquitin-like protein ligase binding | death effector domain binding | identical protein binding | scaffold protein binding | cysteine-type endopeptidase activity | protein binding | ubiquitin protein ligase binding | endopeptidase activity | peptidase activity
GO Biological Process
regulation of cysteine-type endopeptidase activity | response to cytokine | proteolysis | regulation of programmed cell death | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | protein processing | cysteine-type endopeptidase activity involved in apoptotic signaling pathway | cellular process | organic substance catabolic process | extrinsic apoptotic signaling pathway | proteolysis involved in cellular protein catabolic process | zymogen activation | TRAIL-activated apoptotic signaling pathway | negative regulation of signaling | cysteine-type endopeptidase activity involved in apoptotic process | regulation of proteolysis | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | response to stimulus | cellular response to mechanical stimulus | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | positive regulation of cysteine-type endopeptidase activity | execution phase of apoptosis | programmed cell death | cellular protein catabolic process | positive regulation of proteolysis | extrinsic apoptotic signaling pathway via death domain receptors | cysteine-type peptidase activity | positive regulation of macrophage differentiation | apoptotic process | nitrogen compound metabolic process | regulation of signal transduction | regulation of peptidase activity | regulation of catalytic activity | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | positive regulation of hydrolase activity | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | protein maturation | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | cysteine-type endopeptidase activity | apoptotic signaling pathway | positive regulation of molecular function | protein metabolic process | response to organic substance | regulation of hemopoiesis | response to mechanical stimulus | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cellular macromolecule catabolic process | cell surface receptor signaling pathway | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | organic substance metabolic process | cell death | gene expression | organonitrogen compound catabolic process | regulation of cell communication | regulation of macrophage differentiation | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | endopeptidase activity | cellular protein metabolic process | regulation of endopeptidase activity | regulation of developmental process | positive regulation of metabolic process | positive regulation of myeloid leukocyte differentiation | cellular metabolic process | peptidase activity | response to tumor necrosis factor | regulation of cell death | activation of cysteine-type endopeptidase activity | regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process
GO Cellular Component
ripoptosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | plasma membrane protein complex | cytoplasm | death-inducing signaling complex | intracellular organelle | protein-containing complex | CD95 death-inducing signaling complex | nucleoplasm | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane
