QuickView for CAST;jsessionid=A4020CEF757C1DCB68DE526741484CB8;jsessionid=3A898121C3BC0FD85155E072D7F9D53E (gene)

Gene Symbol:

Cast Mus musculus

Full name:

calpastatin

Synonyms:

calpastatin, calpain inhibitor, calpastatin type III

Genomic Location:

Chr 13: 74831734-74945369

Description:

This gene encodes an inhibitor of the calcium-dependent cysteine protease, calpain. This protein plays roles in multiple processes, including apoptosis, cell cycle regulation, and membrane fusion. Multiple protein isoforms exist which contain unique N-terminal domains, and multiple inhibitory domains that share homology with each other. Some isofor...

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This gene encodes an inhibitor of the calcium-dependent cysteine protease, calpain. This protein plays roles in multiple processes, including apoptosis, cell cycle regulation, and membrane fusion. Multiple protein isoforms exist which contain unique N-terminal domains, and multiple inhibitory domains that share homology with each other. Some isoforms may be tissue-specific. Two different pseudogenes of this gene are found on chromosome 19.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ELK1_01 ,  CETS1P54_01 ,  P300_01 ,  YY1_01 ,  CDP_01 ,  GATA1_02 ,  GATA1_04 ,  FOXD3_01 ,  GATA_C ,  HNF1_C ,  CHOP_01 ,  LMO2COM_02 ,  ETS1_B ,  ETS2_B ,  GATA1_05 ,  PAX4_02 ,  FOXJ2_02 ,  CTTTAAR_UNKNOWN ,  GCM_Q2 ,  HNF6_Q6 ,  TEF_Q6 ,  TEL2_Q6 ,  CIZ_01 ,  ETS_Q4 ,  PIT1_Q6 ,  E2A_Q2 ,  GGGYGTGNY_UNKNOWN ,  TTTGCAC_MIR19A_MIR19B ,  GTGACTT_MIR224 ,  ATTCTTT_MIR186 ,  TTTNNANAGCYR_UNKNOWN ,  YGCANTGCR_UNKNOWN ,  CAGCTG_AP4_Q5 ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  RYTTCCTG_ETS2_B ,  MGGAAGTG_GABP_B ,  AAAYWAACM_HFH4_01 ,  YTATTTTNR_MEF2_02 ,  TGACAGNY_MEIS1_01 ,  TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  GGGTGGRR_PAX4_03

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-361 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-140 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-455 ,  Predicted Gene Targets for miR-485-3p ,  Predicted Gene Targets for miR-490 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-500

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