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QuickView for CAST;jsessionid=A4020CEF757C1DCB68DE526741484CB8;jsessionid=51EBAFF20AFD03BC236583C290C977A2 (gene)


Gene Symbol:
Cast Rattus norvegicus Rattus norvegicus
Full name:
calpastatin
Synonyms:
calpastatin, calpain inhibitor
Genomic Location:
Chr 2: 1495048-1608477
Description:
inhibitor of calpain; degradation is required for myoblast fusion; exists in multiple alternatively spliced isoforms
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-103 Predicted Gene Targets for miR-128 Predicted Gene Targets for miR-135 Predicted Gene Targets for miR-15 Predicted Gene Targets for miR-141 Predicted Gene Targets for miR-218 Predicted Gene Targets for miR-24 Predicted Gene Targets for miR-25 Predicted Gene Targets for miR-26 Predicted Gene Targets for miR-299





GO Molecular Function

endopeptidase inhibitor activity | enzyme binding | enzyme inhibitor activity | molecular function regulator | calcium-dependent cysteine-type endopeptidase inhibitor activity | protein binding | peptidase inhibitor activity | enzyme regulator activity | protease binding | cysteine-type endopeptidase inhibitor activity

GO Biological Process

egg activation | brain development | regulation of cell cycle process | myoblast fusion | regulation of cysteine-type endopeptidase activity | endopeptidase inhibitor activity | syncytium formation by plasma membrane fusion | regulation of programmed cell death | negative regulation of cysteine-type endopeptidase activity | negative regulation of cellular process | cell differentiation | nervous system development | negative regulation of proteolysis | cellular process | negative regulation of apoptotic process | regulation of proteolysis | regulation of cell cycle | negative regulation of cell cycle arrest | negative regulation of cellular metabolic process | muscle structure development | muscle cell differentiation | regeneration | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | hepaticobiliary system development | head development | enzyme inhibitor activity | negative regulation of epithelial cell apoptotic process | reproduction | negative regulation of metabolic process | regulation of protein processing | molecular function regulator | system development | reproductive process | multicellular organism development | negative regulation of catalytic activity | syncytium formation | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | positive regulation of cell cycle | regulation of gene expression | regulation of cell cycle arrest | inhibition of cysteine-type endopeptidase activity | liver development | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | fertilization | calcium-dependent cysteine-type endopeptidase inhibitor activity | regulation of epithelial cell apoptotic process | regulation of cellular metabolic process | negative regulation of protein processing | regulation of protein metabolic process | striated muscle cell differentiation | single fertilization | gland development | negative regulation of type B pancreatic cell apoptotic process | anatomical structure development | regulation of protein catabolic process | negative regulation of programmed cell death | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | cell activation | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | negative regulation of protein metabolic process | negative regulation of molecular function | myotube differentiation | myoblast differentiation | peptidase inhibitor activity | enzyme regulator activity | anatomical structure morphogenesis | regulation of endopeptidase activity | developmental process | negative regulation of hydrolase activity | central nervous system development | negative regulation of cell cycle process | regulation of cell death | cysteine-type endopeptidase inhibitor activity | negative regulation of cell death | aging | sexual reproduction | negative regulation of endopeptidase activity | animal organ regeneration | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | synapse | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | endomembrane system | postsynapse | postsynaptic density | asymmetric synapse | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | cytosol | intracellular | membrane