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QuickView for CCND2;jsessionid=32E1057D69E4C2D1715CE26A56C14856;jsessionid=24C9541728335DB7C7D69A1D2B3CAF19;jsessionid=AF4F478EBA9532D326280364D5BA8B21 (gene)


Gene Symbol:
Ccnd2 Rattus norvegicus Rattus norvegicus
Full name:
cyclin D2
Synonyms:
G1/S-specific cyclin-D2, vin-1 proto-oncogene
Genomic Location:
Chr 4: 163523817-163546501
Description:
plays a role in the G1 to S phase transition; involved in regulation of cell proliferation
Orthologs:
Homo sapiens Mus musculus D. melanogaster Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
E47_01 PBX1_01 CDP_02 TAXCREB_01 CEBPB_02 PBX1_02 CREBP1_Q2 STAT_01 LMO2COM_01 MIF1_01
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for let-7 Predicted Gene Targets for miR-1 Predicted Gene Targets for miR-135 Predicted Gene Targets for miR-145 Predicted Gene Targets for miR-15 Predicted Gene Targets for miR-153 Predicted Gene Targets for miR-183 Predicted Gene Targets for miR-186 Predicted Gene Targets for miR-19 Predicted Gene Targets for miR-191


Transcripts Names
NM_022267
Protein Names
Q04827



GO Molecular Function

kinase binding | protein kinase regulator activity | kinase regulator activity | protein kinase binding | enzyme binding | molecular function regulator | catalytic activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | enzyme regulator activity | kinase activity | cyclin-dependent protein serine/threonine kinase regulator activity

GO Biological Process

positive regulation of cyclin-dependent protein serine/threonine kinase activity | response to radiation | cellular response to X-ray | regulation of cell cycle process | long-term memory | regulation of neurogenesis | developmental process involved in reproduction | ovarian follicle development | regulation of cell development | regulation of cell cycle G1/S phase transition | protein kinase regulator activity | gonad development | positive regulation of G1/S transition of mitotic cell cycle | regulation of programmed cell death | female gonad development | response to X-ray | response to hormone | negative regulation of cellular process | cell differentiation | positive regulation of epithelial cell proliferation | male gamete generation | nervous system development | response to drug | regulation of G1/S transition of mitotic cell cycle | neurogenesis | positive regulation of phosphate metabolic process | regulation of organelle organization | generation of neurons | response to antibiotic | response to organophosphorus | cellular process | kinase regulator activity | reproductive system development | response to estradiol | regulation of mitotic nuclear division | multicellular organismal reproductive process | positive regulation of protein kinase activity | negative regulation of apoptotic process | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to peptide hormone | regulation of cell differentiation | gamete generation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | hepaticobiliary system development | positive regulation of cyclin-dependent protein kinase activity | positive regulation of cell cycle phase transition | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | development of primary sexual characteristics | response to stimulus | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | regulation of cell proliferation | response to peptide | regulation of cell cycle phase transition | development of primary female sexual characteristics | reproduction | response to alcohol | cell cycle G1/S phase transition | positive regulation of protein serine/threonine kinase activity | protein modification process | macromolecule modification | molecular function regulator | response to ethanol | response to nitrogen compound | cellular response to hormone stimulus | system development | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | reproductive process | multicellular organism development | cellular response to peptide hormone stimulus | phosphorus metabolic process | response to purine-containing compound | learning or memory | cellular response to insulin stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of neuron differentiation | response to ketone | response to lipid | nervous system process | cellular response to peptide | cell cycle | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular response to radiation | adult locomotory behavior | liver development | regulation of nitrogen compound metabolic process | cognition | locomotory behavior | cell division | regulation of cellular protein metabolic process | phosphorylation | response to toxic substance | mitotic cell cycle phase transition | positive regulation of cell cycle G1/S phase transition | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | response to testosterone | regulation of protein metabolic process | G1/S transition of mitotic cell cycle | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of mitotic cell cycle | positive regulation of molecular function | multicellular organism reproduction | protein metabolic process | positive regulation of protein modification process | response to organic substance | gland development | regulation of kinase activity | response to insulin | anatomical structure development | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | metabolic process | negative regulation of programmed cell death | behavior | protein kinase activity | organic substance metabolic process | animal organ development | positive regulation of kinase activity | cellular response to ionizing radiation | regulation of phosphate metabolic process | response to cAMP | memory | adult behavior | response to organic cyclic compound | regulation of epithelial cell proliferation | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | reproductive structure development | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | positive regulation of cell cycle process | spermatogenesis | cellular protein modification process | response to organonitrogen compound | cell cycle phase transition | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | cellular response to organic substance | regulation of cell death | sex differentiation | negative regulation of cell death | sexual reproduction | regulation of cellular component organization | response to ionizing radiation | cyclin-dependent protein serine/threonine kinase regulator activity | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | catalytic complex | organelle membrane | nuclear membrane | protein kinase complex | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | endomembrane system | nucleoplasm | nuclear envelope | chromatin | cyclin D2-CDK4 complex | transferase complex | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | cytosol | intracellular | membrane