QuickView for CCR5;jsessionid=209C3C273FF0AF88DFACEDAA9667B2E3;jsessionid=AE5C9E469D70260BB7B4B853ABB765A7;jsessionid=47EDDEAD3CCD94303EB11E4AFE85BB5D;jsessionid=55D4E1FBD5244F1C4AEFE917B4FB27A5 (gene)
- Gene Symbol:
- Ccr5
Rattus norvegicus - Full name:
- chemokine (C-C motif) receptor 5
- Synonyms:
- Ckr5, Cmkbr5, C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, MIP-1 alpha receptor, chemokine (C-C) receptor 5
- Genomic Location:
- Chr 8: 128907157-128912272
- Description:
-
G protein-coupled receptor; involved in regulation of leukocyte activation and migration
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
GO Molecular Function
actin binding | cytokine binding | kinase binding | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | G-protein coupled receptor activity | chemokine binding | cytoskeletal protein binding | signaling receptor activity | G-protein coupled chemoattractant receptor activity | cytokine receptor activity | protein binding | C-C chemokine receptor activity | peptide receptor activity | chemokine receptor activity | G-protein coupled peptide receptor activity | C-C chemokine binding | chemokine (C-C motif) ligand 5 binding
GO Biological Process
positive regulation of cell killing | brain development | regulation of interleukin-1 beta production | response to radiation | response to cytokine | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | response to lipopolysaccharide | intracellular signal transduction | calcium ion transmembrane import into cytosol | positive regulation of apoptotic process | regulation of cell development | cytosolic calcium ion transport | regulation of localization | regulation of programmed cell death | defense response to other organism | establishment of localization | neuron death | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | chemokine-mediated signaling pathway | defense response | nervous system development | cellular chemical homeostasis | neurogenesis | positive regulation of interleukin-1 beta secretion | positive regulation of cell adhesion | generation of neurons | positive regulation of protein secretion | cellular process | negative regulation of axonogenesis | regulation of cell motility | localization | cellular homeostasis | metal ion transport | negative regulation of developmental growth | positive regulation of killing of cells of other organism | negative regulation of apoptotic process | negative regulation of cell migration | regulation of neuron projection development | establishment of localization in cell | regulation of cell differentiation | interspecies interaction between organisms | negative regulation of cell motility | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of apoptotic process by virus | cellular response to molecule of bacterial origin | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | MAPK cascade | calcium ion homeostasis | positive regulation of tumor necrosis factor production | head development | G-protein coupled receptor activity | calcium ion transport into cytosol | regulation of peptide secretion | response to stimulus | positive regulation of interleukin-1 beta production | modulation by virus of host process | negative regulation of myeloid cell apoptotic process | signal transduction by protein phosphorylation | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | response to stress | regulation of cell proliferation | negative regulation of neuron projection development | positive regulation of cell-cell adhesion | inflammatory response to antigenic stimulus | cellular localization | divalent metal ion transport | response to alcohol | positive regulation of cytokine secretion | response to molecule of bacterial origin | regulation of protein transport | G-protein coupled receptor signaling pathway | regulation of cellular component size | regulation of axon extension | protein modification process | regulation of peptide transport | regulation of cell adhesion | macromolecule modification | cell-cell signaling | cell chemotaxis | metal ion homeostasis | regulation of fever generation | leukocyte migration | positive regulation of peptide secretion | locomotion | negative regulation of macrophage apoptotic process | regulation of macrophage apoptotic process | response to external biotic stimulus | system development | nitrogen compound metabolic process | negative regulation of growth | multicellular organism development | cell migration | calcium ion transmembrane transport | phosphorus metabolic process | positive regulation of inflammatory response | regulation of axonogenesis | regulation of killing of cells of other organism | positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction | ion transmembrane transport | regulation of acute inflammatory response | regulation of neuron differentiation | regulation of gene expression | cell killing | positive regulation of secretion | response to lipid | modification of morphology or physiology of other organism | cellular ion homeostasis | positive regulation of heat generation | positive regulation of cytosolic calcium ion concentration | regulation of cell migration | response to cholesterol | cytokine-mediated signaling pathway | regulation of cellular component movement | fat cell differentiation | G-protein coupled chemoattractant receptor activity | positive regulation of cell differentiation | second-messenger-mediated signaling | cellular response to cytokine stimulus | negative regulation of sequestering of calcium ion | phosphorylation | positive regulation of interleukin-1 secretion | protein phosphorylation | regulation of tumor necrosis factor production | cation homeostasis | phosphate-containing compound metabolic process | cytokine receptor activity | response to bacterium | regulation of interleukin-1 production | cellular cation homeostasis | cell communication | positive regulation of interleukin-1 production | inflammatory response | cellular calcium ion homeostasis | defense response to bacterium | homeostatic process | positive regulation of establishment of protein localization | regulation of locomotion | positive regulation of transport | viral process | negative regulation of cell growth | release of sequestered calcium ion into cytosol | calcium-mediated signaling | regulation of cytokine secretion | cation transmembrane transport | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of establishment of protein localization | regulation of growth | response to organic substance | negative regulation of cell projection organization | killing of cells of other organism | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | metabolic process | positive regulation of cell development | regulation of interleukin-1 beta secretion | negative regulation of programmed cell death | negative regulation of axon extension | chemical homeostasis | calcium ion transport | regulation of secretion | positive regulation of cell death | regulation of myeloid cell apoptotic process | positive regulation of interleukin-6 production | immune response | organic substance metabolic process | regulation of sequestering of calcium ion | positive regulation of acute inflammatory response | cell death | animal organ development | forebrain development | negative regulation of neuron differentiation | negative regulation of cellular component movement | regulation of protein secretion | positive regulation of programmed cell death | ion homeostasis | inorganic cation transmembrane transport | positive regulation of cytokine production | positive regulation of protein transport | C-C chemokine receptor activity | positive regulation of fever generation | transmembrane transport | chemokine receptor activity | signaling | G-protein coupled peptide receptor activity | response to organic cyclic compound | sarcoplasmic reticulum calcium ion transport | regulation of developmental growth | negative regulation of leukocyte apoptotic process | cellular protein metabolic process | regulation of cell size | regulation of cytokine production | release of sequestered calcium ion into cytosol by endoplasmic reticulum | cation transport | response to biotic stimulus | regulation of nervous system development | regulation of developmental process | developmental process | regulation of cell growth | cellular protein modification process | regulation of transport | modulation by virus of host morphology or physiology | negative regulation of cell proliferation | regulation of cell-cell adhesion | negative regulation of neural precursor cell proliferation | cellular metal ion homeostasis | central nervous system development | positive regulation of metabolic process | positive regulation of neuron differentiation | ion transport | regulation of cell projection organization | immune system process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | negative regulation of cell development | regulation of interleukin-6 production | regulation of inflammatory response | aging | chemotaxis | divalent inorganic cation homeostasis | negative regulation of locomotion | negative regulation of cell differentiation | regulation of cellular component organization | response to ionizing radiation | response to other organism | signal transduction | positive regulation of gene expression | cellular response to lipopolysaccharide | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
integral component of membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | endomembrane system | plasma membrane | vesicle | endosome | membrane-bounded organelle | organelle | cell periphery | intracellular vesicle | cell surface | intracellular | membrane
