QuickView for CD3H;jsessionid=2DF44C223C6D0B1609B5FFA8C664CA15;jsessionid=22D2C6F9D463DA909F66732C3E64322B;jsessionid=4244FF8B135E0D37C030D266D991847B;jsessionid=D7F72CBC5A47E3CFCF0FB6E1DA558F90 (gene)
- Gene Symbol:
- Cd247
Rattus norvegicus - Full name:
- Cd247 molecule
- Synonyms:
- Cd3z, TCRzeta, T-cell surface glycoprotein CD3 zeta chain, CD247 antigen, CD3 antigen, zeta polypeptide, T-cell receptor CD3, subunit zeta
- Genomic Location:
- Chr 13: 81515383-81594699
- Description:
-
component of T cell receptor (TCR) complex that plays a role in TCR assembly and signaling; does not promote surface expression of Fc gamma RIII, unlike human homolog
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
kinase binding | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | signaling receptor activity | identical protein binding | protein tyrosine kinase binding | protein binding | protein homodimerization activity | protein dimerization activity
GO Biological Process
positive regulation of immune response | protein homooligomerization | immune response-regulating signaling pathway | regulation of cellular localization | regulation of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | immune response-activating cell surface receptor signaling pathway | T cell receptor signaling pathway | cellular process | regulation of immune response | regulation of cellular process | cellular component organization | response to stimulus | regulation of cellular protein localization | positive regulation of immune system process | positive regulation of cellular protein localization | protein homotrimerization | interleukin-2 production | immune response-activating signal transduction | cellular component assembly | protein complex oligomerization | regulation of protein localization to cell surface | positive regulation of protein localization to cell surface | protein homotetramerization | protein tetramerization | cell communication | protein trimerization | cytokine production | protein-containing complex assembly | activation of immune response | cell surface receptor signaling pathway | antigen receptor-mediated signaling pathway | signaling | immune system process | regulation of protein localization | signal transduction | multicellular organismal process
GO Cellular Component
integral component of membrane | T cell receptor complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | receptor complex | protein-containing complex | alpha-beta T cell receptor complex | plasma membrane | cell periphery | intracellular | membrane
