QuickView for CDK1;jsessionid=FDC254472F01E5AD9D3E651E53540CC0;jsessionid=FB8CF97D3E7605827E18909AA4589E75;jsessionid=9850870B1AFDF405E41B42F1C121F05E (gene)
- Gene Symbol:
- Cdk1
Rattus norvegicus - Full name:
- cyclin-dependent kinase 1
- Synonyms:
- Cdc2, Cdc2a, cyclin-dependent kinase 1, Cell division cycle control protein 2, cell division control protein 2 homolog, cell division cycle 2 homolog A, cell division cycle 2, G1 to S and G2 to M, cell division protein kinase 1, p34 protein kinase
- Genomic Location:
- Chr 20: 20018044-20044030
- Description:
-
putative cell cycle control protein; homologous to S. pombe Cdc2
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cyclin binding | ribonucleotide binding | nucleotide binding | cyclin-dependent protein kinase activity | carbohydrate derivative binding | protein serine/threonine kinase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | chromatin binding | ATP binding | Hsp70 protein binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | histone kinase activity | cyclin-dependent protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heat shock protein binding | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | regulation of intracellular protein transport | regulation of cellular localization | muscle tissue development | positive regulation of ATP metabolic process | regulation of localization | positive regulation of striated muscle tissue development | regulation of programmed cell death | peptidyl-amino acid modification | positive regulation of G2/M transition of mitotic cell cycle | negative regulation of cellular process | positive regulation of developmental process | response to metal ion | histone modification | regulation of heart growth | regulation of protein import | cell differentiation | striated muscle cell development | response to drug | positive regulation of phosphate metabolic process | regulation of DNA replication | cardiac cell development | response to antibiotic | regulation of cardiac muscle cell proliferation | positive regulation of oxidative phosphorylation | positive regulation of cellular biosynthetic process | cellular process | localization | chromatin organization | mitotic DNA integrity checkpoint | protein localization to kinetochore | regulation of striated muscle tissue development | macromolecule localization | negative regulation of apoptotic process | endomembrane system organization | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | response to inorganic substance | tissue development | regulation of oxidative phosphorylation | muscle structure development | muscle cell differentiation | regeneration | response to hydrogen peroxide | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cell cycle phase transition | ventricular cardiac muscle cell development | epithelium development | regulation of G2/M transition of mitotic cell cycle | cellular component organization | Golgi inheritance | response to stimulus | peptidyl-threonine phosphorylation | regulation of mitochondrial ATP synthesis coupled electron transport | cyclin-dependent protein kinase activity | muscle cell development | regulation of cellular protein localization | regulation of mitotic cell cycle phase transition | response to stress | negative regulation of G2/M transition of mitotic cell cycle | positive regulation of cellular protein localization | regulation of cell proliferation | mitotic G2 DNA damage checkpoint | cardiac muscle tissue development | regulation of cell cycle phase transition | protein serine/threonine kinase activity | programmed cell death | cellular localization | response to alcohol | cellular response to toxic substance | regulation of protein transport | cellular component assembly | protein modification process | RNA polymerase II CTD heptapeptide repeat kinase activity | regulation of peptide transport | macromolecule modification | regulation of intracellular transport | response to ethanol | response to nitrogen compound | apoptotic process | regulation of cell cycle G2/M phase transition | system development | nitrogen compound metabolic process | negative regulation of mitotic cell cycle phase transition | cellular response to antibiotic | mitotic DNA damage checkpoint | multicellular organism development | negative regulation of cell cycle G2/M phase transition | response to activity | positive regulation of DNA replication | phosphorus metabolic process | cellular response to DNA damage stimulus | positive regulation of muscle organ development | cellular response to oxidative stress | regulation of phosphorylation | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | cellular response to stress | cell cycle | chromosome condensation | positive regulation of intracellular protein transport | regulation of protein import into nucleus, translocation | positive regulation of cellular metabolic process | response to axon injury | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | cardiocyte differentiation | positive regulation of cell cycle G2/M phase transition | response to oxidative stress | protein localization to organelle | Golgi disassembly | positive regulation of cellular respiration | cell proliferation | positive regulation of protein localization to nucleus | response to cadmium ion | positive regulation of cardiac muscle cell proliferation | cell division | cardiac muscle cell development | phosphorylation | response to toxic substance | mitotic cell cycle phase transition | protein phosphorylation | phosphate-containing compound metabolic process | cellular response to drug | striated muscle tissue development | regulation of cellular metabolic process | heart development | positive regulation of cell proliferation | positive regulation of establishment of protein localization | histone phosphorylation | positive regulation of transport | striated muscle cell differentiation | cell aging | regulation of mitotic cell cycle | organelle disassembly | regulation of nucleocytoplasmic transport | mitotic G2/M transition checkpoint | protein-containing complex assembly | positive regulation of organ growth | protein metabolic process | regulation of establishment of protein localization | regulation of growth | response to organic substance | regulation of cardiac muscle tissue development | regulation of protein import into nucleus | histone kinase activity | regulation of cellular respiration | Golgi organization | protein localization to chromosome, centromeric region | response to wounding | cyclin-dependent protein serine/threonine kinase activity | anatomical structure development | response to amine | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | metabolic process | negative regulation of programmed cell death | negative regulation of mitotic cell cycle | cellular protein localization | cellular response to hydrogen peroxide | protein kinase activity | cellular response to reactive oxygen species | organic substance metabolic process | response to copper ion | cell death | animal organ development | response to reactive oxygen species | regulation of ATP metabolic process | regulation of phosphate metabolic process | DNA packaging | positive regulation of muscle tissue development | positive regulation of intracellular transport | positive regulation of protein transport | negative regulation of cell cycle | cardiac muscle cell differentiation | positive regulation of protein import into nucleus, translocation | positive regulation of developmental growth | covalent chromatin modification | positive regulation of growth | response to organic cyclic compound | cell development | regulation of developmental growth | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | cellular macromolecule localization | positive regulation of protein import into nucleus | regulation of organ growth | regulation of developmental process | positive regulation of DNA metabolic process | kinase activity | organelle inheritance | developmental process | organelle organization | positive regulation of protein import | positive regulation of cell cycle process | peptidyl-serine phosphorylation | cellular protein modification process | regulation of transport | positive regulation of heart growth | DNA conformation change | response to organonitrogen compound | cell cycle phase transition | ventricular cardiac muscle cell differentiation | epithelial cell differentiation | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | chromosome organization | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | regulation of protein localization | regulation of cell death | positive regulation of cardiac muscle tissue development | DNA damage checkpoint | cell cycle checkpoint | negative regulation of cell death | circulatory system development | aging | positive regulation of nucleocytoplasmic transport | protein localization to chromosome | animal organ regeneration | positive regulation of gene expression | regulation of muscle organ development | macromolecule metabolic process | positive regulation of mitochondrial ATP synthesis coupled electron transport | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | cyclin B1-CDK1 complex | mitochondrial matrix | intracellular membrane-bounded organelle | catalytic complex | microtubule organizing center | protein kinase complex | cell | microtubule | cytoplasm | spindle | intracellular organelle | centrosome | protein-containing complex | midbody | transferase complex | microtubule cytoskeleton | mitochondrion | spindle microtubule | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | cytosol | cytoskeleton | intracellular | mitotic spindle | supramolecular complex
