QuickView for CDK1;jsessionid=FDC254472F01E5AD9D3E651E53540CC0;jsessionid=070245F51BAA625AF1ADE2560406015B (gene)
- Gene Symbol:
- Cdk1
Mus musculus - Full name:
- cyclin-dependent kinase 1
- Synonyms:
- Cdc2, Cdc2a, p34<CDC2>, cyclin-dependent kinase 1, cell cycle p34 CDC2 kinase protein, cell division control protein 2 homolog, cell division cycle 2 homolog A, cell division cycle control protein 2a, cell division protein kinase 1, p34 protein kinase
- Genomic Location:
- Chr 10: 68799383-68815660
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cyclin binding | ribonucleotide binding | nucleotide binding | cyclin-dependent protein kinase activity | carbohydrate derivative binding | protein serine/threonine kinase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | chromatin binding | ATP binding | Hsp70 protein binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | histone kinase activity | cyclin-dependent protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heat shock protein binding | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | regulation of intracellular protein transport | regulation of cellular localization | positive regulation of ATP metabolic process | regulation of localization | positive regulation of striated muscle tissue development | regulation of programmed cell death | peptidyl-amino acid modification | positive regulation of G2/M transition of mitotic cell cycle | negative regulation of cellular process | positive regulation of developmental process | histone modification | regulation of heart growth | regulation of protein import | response to drug | positive regulation of phosphate metabolic process | regulation of DNA replication | response to antibiotic | regulation of cardiac muscle cell proliferation | positive regulation of oxidative phosphorylation | positive regulation of cellular biosynthetic process | cellular process | localization | chromatin organization | mitotic DNA integrity checkpoint | protein localization to kinetochore | regulation of striated muscle tissue development | macromolecule localization | negative regulation of apoptotic process | endomembrane system organization | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of oxidative phosphorylation | regeneration | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cell cycle phase transition | regulation of G2/M transition of mitotic cell cycle | cellular component organization | Golgi inheritance | response to stimulus | peptidyl-threonine phosphorylation | regulation of mitochondrial ATP synthesis coupled electron transport | cyclin-dependent protein kinase activity | regulation of cellular protein localization | regulation of mitotic cell cycle phase transition | response to stress | negative regulation of G2/M transition of mitotic cell cycle | positive regulation of cellular protein localization | regulation of cell proliferation | mitotic G2 DNA damage checkpoint | regulation of cell cycle phase transition | protein serine/threonine kinase activity | programmed cell death | cellular localization | response to alcohol | regulation of protein transport | cellular component assembly | protein modification process | RNA polymerase II CTD heptapeptide repeat kinase activity | regulation of peptide transport | macromolecule modification | regulation of intracellular transport | response to ethanol | response to nitrogen compound | apoptotic process | regulation of cell cycle G2/M phase transition | system development | nitrogen compound metabolic process | negative regulation of mitotic cell cycle phase transition | mitotic DNA damage checkpoint | multicellular organism development | negative regulation of cell cycle G2/M phase transition | positive regulation of DNA replication | phosphorus metabolic process | cellular response to DNA damage stimulus | positive regulation of muscle organ development | regulation of phosphorylation | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of gene expression | cellular response to stress | cell cycle | chromosome condensation | positive regulation of intracellular protein transport | regulation of protein import into nucleus, translocation | positive regulation of cellular metabolic process | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | positive regulation of cell cycle G2/M phase transition | protein localization to organelle | Golgi disassembly | positive regulation of cellular respiration | cell proliferation | positive regulation of protein localization to nucleus | positive regulation of cardiac muscle cell proliferation | cell division | phosphorylation | response to toxic substance | mitotic cell cycle phase transition | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | histone phosphorylation | positive regulation of transport | cell aging | regulation of mitotic cell cycle | organelle disassembly | regulation of nucleocytoplasmic transport | mitotic G2/M transition checkpoint | protein-containing complex assembly | positive regulation of organ growth | protein metabolic process | regulation of establishment of protein localization | regulation of growth | response to organic substance | regulation of cardiac muscle tissue development | regulation of protein import into nucleus | histone kinase activity | regulation of cellular respiration | Golgi organization | protein localization to chromosome, centromeric region | cyclin-dependent protein serine/threonine kinase activity | anatomical structure development | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | metabolic process | negative regulation of programmed cell death | negative regulation of mitotic cell cycle | cellular protein localization | protein kinase activity | organic substance metabolic process | cell death | animal organ development | regulation of ATP metabolic process | regulation of phosphate metabolic process | DNA packaging | positive regulation of muscle tissue development | positive regulation of intracellular transport | positive regulation of protein transport | negative regulation of cell cycle | positive regulation of protein import into nucleus, translocation | positive regulation of developmental growth | covalent chromatin modification | positive regulation of growth | regulation of developmental growth | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | cellular macromolecule localization | positive regulation of protein import into nucleus | regulation of organ growth | regulation of developmental process | positive regulation of DNA metabolic process | kinase activity | organelle inheritance | developmental process | organelle organization | positive regulation of protein import | positive regulation of cell cycle process | peptidyl-serine phosphorylation | cellular protein modification process | regulation of transport | positive regulation of heart growth | DNA conformation change | response to organonitrogen compound | cell cycle phase transition | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | chromosome organization | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | regulation of protein localization | regulation of cell death | positive regulation of cardiac muscle tissue development | DNA damage checkpoint | cell cycle checkpoint | negative regulation of cell death | aging | positive regulation of nucleocytoplasmic transport | protein localization to chromosome | animal organ regeneration | positive regulation of gene expression | regulation of muscle organ development | macromolecule metabolic process | positive regulation of mitochondrial ATP synthesis coupled electron transport | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | cyclin B1-CDK1 complex | mitochondrial matrix | intracellular membrane-bounded organelle | catalytic complex | microtubule organizing center | protein kinase complex | cell | microtubule | cytoplasm | spindle | intracellular organelle | centrosome | protein-containing complex | midbody | transferase complex | microtubule cytoskeleton | mitochondrion | spindle microtubule | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | cytosol | cytoskeleton | intracellular | mitotic spindle | supramolecular complex
