QuickView for CDK2;jsessionid=FC0FB3AEC80DA2F002DCF51A6517AAC8;jsessionid=6EE41D93BF0EFB08F52A5EA248E66113;jsessionid=FA572CBBFEF4A2A14AA1B0182D63BC2A;jsessionid=67CA06B2821C1B5A3258B089FEB7DBA8 (gene)
- Gene Symbol:
- cdc2
Schizosaccharomyces pombe - Full name:
- cyclin-dependent protein kinase Cdc2
- Synonyms:
- SPBC11B10.09, swo2
- Genomic Location:
- Chr II: 1500340-1501528
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cyclin binding | ribonucleotide binding | nucleotide binding | cyclin-dependent protein kinase activity | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | cyclin-dependent protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
negative regulation of exit from mitosis | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | negative regulation of cell division | regulation of intracellular protein transport | positive regulation of Ras protein signal transduction | positive regulation of cellular component organization | regulation of cellular localization | negative regulation of conjugation with cellular fusion | regulation of localization | regulation of meiotic cell cycle | establishment of localization | regulation of nuclear cell cycle DNA replication | response to mitotic G2 DNA damage checkpoint signaling | negative regulation of cellular process | regulation of protein import | positive regulation of protein catabolic process | response to DNA damage checkpoint signaling | positive regulation of DNA recombination | regulation of DNA replication | regulation of organelle organization | negative regulation of DNA metabolic process | regulation of DNA repair | negative regulation of proteolysis | regulation of attachment of spindle microtubules to kinetochore | regulation of chromosome segregation | positive regulation of cellular biosynthetic process | cellular process | establishment of organelle localization | localization | negative regulation of ubiquitin-dependent protein catabolic process | cytokinetic process | regulation of exit from mitosis | positive regulation of double-strand break repair via homologous recombination | regulation of mitotic nuclear division | regulation of chromosome separation | negative regulation of mitotic spindle elongation | regulation of cytokinesis, actomyosin contractile ring assembly | negative regulation of chromosome segregation | regulation of proteolysis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | regulation of mitotic spindle organization | establishment of localization in cell | negative regulation of cellular metabolic process | regulation of binding | positive regulation of cytokinesis | regulation of cellular process | regulation of metabolic process | positive regulation of nuclear cell cycle DNA replication | regulation of mitotic cytokinetic process | organelle localization | negative regulation of DNA repair | positive regulation of cell cycle phase transition | positive regulation of cellular protein metabolic process | regulation of attachment of mitotic spindle microtubules to kinetochore | regulation of G2/M transition of mitotic cell cycle | cellular component organization | positive regulation of response to DNA damage stimulus | establishment of chromosome localization | negative regulation of cytokinesis | regulation of cell division | negative regulation of cellular protein catabolic process | negative regulation of DNA replication | positive regulation of cellular protein catabolic process | response to stimulus | cyclin-dependent protein kinase activity | regulation of DNA recombination | regulation of cellular protein localization | regulation of mitotic cell cycle phase transition | chromosome segregation | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | negative regulation of mitotic cytokinesis | positive regulation of cellular protein localization | response to mitotic DNA integrity checkpoint signaling | regulation of cell proliferation | regulation of double-strand break repair | regulation of cell cycle phase transition | protein serine/threonine kinase activity | regulation of metaphase plate congression | regulation of transcription regulatory region DNA binding | cellular localization | cell cycle G1/S phase transition | regulation of DNA binding | regulation of protein transport | positive regulation of meiotic cell cycle | negative regulation of metabolic process | protein modification process | regulation of peptide transport | macromolecule modification | regulation of intracellular transport | regulation of chromosome condensation | regulation of cellular response to stress | regulation of cell cycle G2/M phase transition | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | positive regulation of organelle organization | regulation of actin cytoskeleton organization | positive regulation of mitotic metaphase/anaphase transition | positive regulation of chromosome separation | positive regulation of DNA replication | sister chromatid segregation | phosphorus metabolic process | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of actomyosin structure organization | regulation of mitotic cytokinesis | positive regulation of chromosome organization | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of small GTPase mediated signal transduction | positive regulation of septation initiation signaling | cell cycle | positive regulation of intracellular protein transport | positive regulation of cellular metabolic process | negative regulation of anaphase-promoting complex-dependent catabolic process | mitotic metaphase plate congression | regulation of protein localization to nucleus | regulation of mitotic sister chromatid separation | regulation of nitrogen compound metabolic process | regulation of DNA-dependent DNA replication initiation | positive regulation of intracellular signal transduction | negative regulation of DNA binding | negative regulation of binding | negative regulation of mitotic DNA replication initiation | negative regulation of mitotic nuclear division | negative regulation of double-strand break repair | negative regulation of double-strand break repair via nonhomologous end joining | positive regulation of protein localization to nucleus | correction of merotelic kinetochore attachment, mitotic | cell division | regulation of actomyosin contractile ring contraction | metaphase plate congression | regulation of cellular protein metabolic process | negative regulation of transcription regulatory region DNA binding | G2/M transition of mitotic cell cycle | cytokinesis | phosphorylation | negative regulation of mitotic actomyosin contractile ring assembly | regulation of DNA-dependent DNA replication | mitotic cell cycle phase transition | protein phosphorylation | phosphate-containing compound metabolic process | response to intra-S DNA damage checkpoint signaling | nuclear chromosome segregation | negative regulation of protein binding | regulation of cellular metabolic process | negative regulation of mitotic sister chromatid segregation | regulation of cytokinesis | regulation of protein metabolic process | positive regulation of signal transduction | cell cycle G2/M phase transition | G1/S transition of mitotic cell cycle | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of mitotic spindle elongation | positive regulation of transport | positive regulation of division septum assembly | regulation of double-strand break repair via nonhomologous end joining | regulation of double-strand break repair via homologous recombination | positive regulation of mitotic chromosome condensation | regulation of mitotic cell cycle | regulation of microtubule-based process | regulation of nucleocytoplasmic transport | regulation of proteasomal ubiquitin-dependent protein catabolic process | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | protein metabolic process | regulation of establishment of protein localization | negative regulation of DNA-dependent DNA replication | regulation of protein import into nucleus | cyclin-dependent protein serine/threonine kinase activity | regulation of intracellular signal transduction | regulation of sister chromatid segregation | positive regulation of double-strand break repair | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | positive regulation of small GTPase mediated signal transduction | nuclear division | metabolic process | regulation of protein catabolic process | regulation of proteasomal protein catabolic process | negative regulation of cytoskeleton organization | negative regulation of mitotic cell cycle | regulation of response to DNA damage stimulus | protein kinase activity | positive regulation of cellular component biogenesis | positive regulation of DNA-dependent DNA replication | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of cellular protein metabolic process | positive regulation of chromosome segregation | regulation of chromosome organization | negative regulation of attachment of mitotic spindle microtubules to kinetochore | mitotic nuclear division | positive regulation of intracellular transport | positive regulation of exit from mitosis | positive regulation of protein transport | negative regulation of cell cycle | negative regulation of protein catabolic process | negative regulation of protein metabolic process | regulation of mitotic sister chromatid segregation | positive regulation of mitotic cytokinetic process | regulation of cell communication | negative regulation of chromosome organization | negative regulation of molecular function | positive regulation of mitotic cell cycle DNA replication | negative regulation of DNA-dependent DNA replication initiation | regulation of protein binding | cellular protein metabolic process | regulation of Ras protein signal transduction | positive regulation of protein import into nucleus | response to biotic stimulus | positive regulation of DNA metabolic process | regulation of RNA polymerase II regulatory region sequence-specific DNA binding | kinase activity | organelle organization | negative regulation of mitotic cell cycle DNA replication | positive regulation of protein import | positive regulation of cell cycle process | cellular protein modification process | positive regulation of mitotic sister chromatid separation | regulation of transport | regulation of mitotic metaphase/anaphase transition | positive regulation of mitotic cytokinesis | cell cycle phase transition | positive regulation of metabolic process | regulation of actin filament-based process | chromosome organization | cellular metabolic process | negative regulation of mitotic telomere tethering at nuclear periphery | negative regulation of cell cycle process | regulation of protein localization | regulation of division septum assembly | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | positive regulation of nucleocytoplasmic transport | mitotic sister chromatid segregation | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | regulation of mitotic chromosome condensation | regulation of cytoskeleton organization | positive regulation of signaling | positive regulation of mitotic nuclear division | regulation of signaling | positive regulation of DNA repair | macromolecule metabolic process | regulation of mitotic DNA replication initiation | negative regulation of proteasomal protein catabolic process
GO Cellular Component
mitotic spindle midzone | chromosome | intracellular membrane-bounded organelle | catalytic complex | nuclear telomeric heterochromatin | microtubule organizing center | chromosome, centromeric region | protein kinase complex | cell | nuclear lumen | cytoplasm | spindle | intracellular organelle | meiotic spindle pole body | protein-containing complex | chromatin | nuclear chromosome | transferase complex | microtubule cytoskeleton | chromosome, telomeric region | spindle midzone | serine/threonine protein kinase complex | membrane-bounded organelle | heterochromatin | nucleus | organelle | nuclear heterochromatin | spindle pole body | mitotic spindle pole body | membrane-enclosed lumen | telomeric heterochromatin | cyclin-dependent protein kinase holoenzyme complex | nuclear chromatin | cytoskeleton | nuclear chromosome, telomeric region | intracellular | mitotic spindle
