QuickView for CDK5;jsessionid=DF00B73361DF4175895E59E85F89AE6E;jsessionid=2CBBD702BD5C63F37C03A962A5CEFC1B (gene)
- Gene Symbol:
- Cdk5
Mus musculus - Full name:
- cyclin-dependent kinase 5
- Synonyms:
- AW048668, Crk6, cyclin-dependent-like kinase 5, CR6 protein kinase, TPKII catalytic subunit, cell division protein kinase 5, serine/threonine-protein kinase PSSALRE, tau protein kinase II catalytic subunit
- Genomic Location:
- Chr 5: 23924060-23929348
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Gallus gallus , Schizosaccharomyces pombe , Bos taurus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
E47_01 , AACTTT_UNKNOWN , LYF1_01 , CHOP_01 , ZF5_B , MSX1_01 , NERF_Q2 , MAF_Q6 , SMAD3_Q6 , GCTNWTTGK_UNKNOWN
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
tau-protein kinase activity | ephrin receptor binding | kinase binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | acetylcholine receptor regulator activity | cyclin-dependent protein kinase activity | signaling receptor binding | carbohydrate derivative binding | protein serine/threonine kinase activity | molecular function regulator | catalytic activity | ErbB-3 class receptor binding | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | p53 binding | purine nucleotide binding | acetylcholine receptor activator activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | receptor regulator activity | cyclin-dependent protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | Hsp90 protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heat shock protein binding | ErbB-2 class receptor binding | heterocyclic compound binding | receptor activator activity | small molecule binding
GO Biological Process
maintenance of protein location in nucleus | tau-protein kinase activity | brain development | response to radiation | cell morphogenesis | negative regulation of intracellular transport | serine phosphorylation of STAT protein | regulation of intracellular protein transport | actin filament-based process | exocytosis | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | regulation of cellular localization | muscle tissue development | positive regulation of apoptotic process | regulation of cell development | regulation of localization | cell-substrate adhesion | regulation of programmed cell death | peptidyl-amino acid modification | Schwann cell differentiation | hippocampus development | actin cytoskeleton organization | establishment of localization | neuron death | negative regulation of neuron death | neuron migration | negative regulation of cellular process | negative regulation of RNA biosynthetic process | regulation of protein localization to membrane | cell differentiation | excitatory postsynaptic potential | positive regulation of signaling receptor activity | nervous system development | response to drug | positive regulation of glial cell apoptotic process | cerebellum morphogenesis | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | intracellular transport | negative regulation of proteolysis | regulation of neuron death | calcium ion import | cellular process | secretion | negative regulation of axonogenesis | peripheral nervous system development | organic substance catabolic process | establishment of organelle localization | regulation of cell motility | regulation of dendritic spine morphogenesis | localization | cell projection morphogenesis | protein transport | forebrain cell migration | metal ion transport | visual learning | chemical synaptic transmission | neuron development | negative regulation of developmental growth | central nervous system neuron differentiation | synapse assembly | negative regulation of nucleic acid-templated transcription | learning | positive regulation of protein kinase activity | macromolecule localization | axon guidance | regulation of proteolysis | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | regulation of protein export from nucleus | establishment of localization in cell | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of cell differentiation | muscle structure development | skeletal muscle organ development | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | gliogenesis | catabolic process | organelle localization | cortical actin cytoskeleton organization | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | positive regulation of protein binding | head development | acetylcholine receptor regulator activity | associative learning | response to stimulus | peptidyl-threonine phosphorylation | negative regulation of protein transport | cyclin-dependent protein kinase activity | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | metencephalon development | cerebral cortex radial glia guided migration | positive regulation of protein metabolic process | response to cocaine | negative regulation of intracellular protein transport | response to stress | neuron projection guidance | intracellular protein transport | positive regulation of cellular protein localization | skeletal muscle tissue development | negative regulation of neuron projection development | regulation of protein ubiquitination | response to peptide | protein localization to nucleus | telencephalon cell migration | receptor clustering | protein serine/threonine kinase activity | programmed cell death | regulation of neurotransmitter receptor activity | cellular localization | divalent metal ion transport | secretion by cell | rhythmic process | maintenance of protein localization in organelle | negative regulation of transport | regulation of protein transport | negative regulation of metabolic process | regulation of cellular component size | cellular component assembly | regulation of axon extension | protein modification process | regulation of synapse structure or activity | regulation of peptide transport | modulation of chemical synaptic transmission | mitochondrion organization | macromolecule modification | cell-cell signaling | synaptic transmission, dopaminergic | regulation of intracellular transport | molecular function regulator | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | regulation of membrane potential | positive regulation of exocytosis | locomotion | response to nitrogen compound | central nervous system neuron development | apoptotic process | synaptic vesicle cycle | response to light stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of growth | multicellular organism development | cell migration | regulation of synaptic transmission, glutamatergic | phosphorus metabolic process | learning or memory | regulation of axonogenesis | regulation of catalytic activity | cerebellum development | regulation of phosphorylation | negative regulation of cellular protein localization | localization within membrane | synaptic vesicle recycling | telencephalon development | regulation of neuron differentiation | regulation of gene expression | regulation of postsynaptic membrane potential | protein localization to membrane | axon development | positive regulation of secretion | organic substance transport | nervous system process | cellular response to peptide | cell cycle | synaptic signaling | positive regulation of intracellular protein transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | response to ammonium ion | regulation of synapse organization | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | glial cell migration | neuron apoptotic process | peptide transport | vesicle-mediated transport | regulation of cellular component movement | synapse organization | axonogenesis | protein localization to organelle | behavioral response to cocaine | synaptic transmission, glutamatergic | cognition | acetylcholine receptor activator activity | establishment of vesicle localization | cell division | sensory perception of pain | regulation of cellular protein metabolic process | glial cell differentiation | hindbrain development | phosphorylation | regulated exocytosis | positive regulation of neuron death | negative regulation of protein export from nucleus | cerebral cortex cell migration | response to xenobiotic stimulus | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | positive regulation of regulated secretory pathway | maintenance of protein location | protein localization to synapse | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of protein localization to membrane | regulation of neuron apoptotic process | synaptic vesicle endocytosis | cellular response to amyloid-beta | cerebellar cortex morphogenesis | regulation of protein metabolic process | limbic system development | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | negative regulation of protein ubiquitination | positive regulation of transport | cerebral cortex development | negative regulation of cell growth | positive regulation of molecular function | regulation of nucleocytoplasmic transport | neuron differentiation | regulation of signaling receptor activity | receptor regulator activity | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | regulation of growth | response to organic substance | receptor catabolic process | negative regulation of cell projection organization | visual behavior | regulation of JAK-STAT cascade | regulation of kinase activity | response to wounding | import into cell | cyclin-dependent protein serine/threonine kinase activity | regulation of intracellular signal transduction | regulation of exocytosis | positive regulation of neuron apoptotic process | anatomical structure development | Schwann cell development | regulation of dendrite morphogenesis | negative regulation of synaptic plasticity | cell surface receptor signaling pathway | cell projection organization | metabolic process | positive regulation of calcium ion-dependent exocytosis | regulation of protein localization to plasma membrane | regulation of protein targeting | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | cellular protein localization | oligodendrocyte differentiation | cerebellar cortex development | amide transport | regulation of vesicle-mediated transport | negative regulation of axon extension | hindbrain morphogenesis | calcium ion transport | endocytosis | regulation of secretion | behavior | positive regulation of cell death | cell adhesion | protein kinase activity | neuron projection development | organic substance metabolic process | nuclear transport | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | cerebral cortex radially oriented cell migration | forebrain development | negative regulation of neuron differentiation | pallium development | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | positive regulation of kinase activity | maintenance of protein location in cell | regulation of phosphate metabolic process | cytoskeleton organization | response to alkaloid | positive regulation of binding | establishment of protein localization | regulation of regulated secretory pathway | positive regulation of intracellular transport | regulation of postsynapse organization | positive regulation of protein transport | dendrite morphogenesis | anatomical structure formation involved in morphogenesis | negative regulation of cell cycle | adult behavior | negative regulation of protein metabolic process | regulation of dendrite development | sensory perception | cerebellar cortex formation | regulation of cell communication | regulation of dendritic spine development | signaling | response to amyloid-beta | regulation of transcription, DNA-templated | cell-matrix adhesion | regulation of protein binding | glial cell development | response to organic cyclic compound | cell development | regulation of developmental growth | synaptic vesicle localization | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cell size | anatomical structure morphogenesis | cation transport | cellular macromolecule localization | nucleocytoplasmic transport | dendrite development | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | layer formation in cerebral cortex | organelle organization | regulation of cell growth | peptidyl-serine phosphorylation | cellular protein modification process | positive regulation of protein targeting to membrane | cortical cytoskeleton organization | regulation of transport | receptor metabolic process | response to organonitrogen compound | regulation of calcium ion-dependent exocytosis | central nervous system development | response to anesthetic | positive regulation of metabolic process | regulation of synaptic plasticity | vesicle localization | ion transport | regulation of cell projection organization | corpus callosum development | cellular metabolic process | synaptic vesicle transport | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | negative regulation of cell development | chemotaxis | receptor activator activity | motor neuron axon guidance | negative regulation of cell differentiation | regulation of cellular component organization | muscle organ development | signal transduction | regulation of signaling | macromolecule metabolic process | negative regulation of neurogenesis | maintenance of location in cell | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | dendrite | intracellular membrane-bounded organelle | synapse | catalytic complex | neuron projection | somatodendritic compartment | neuromuscular junction | cell body | protein kinase complex | actin-based cell projection | cell | nuclear lumen | neuronal cell body | distal axon | synaptic membrane | nucleolus | lamellipodium | microtubule | cytoplasm | intracellular organelle | dendritic tree | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | cell leading edge | transferase complex | postsynaptic density | microtubule cytoskeleton | asymmetric synapse | site of polarized growth | serine/threonine protein kinase complex | membrane-bounded organelle | filopodium | nucleus | organelle | postsynaptic specialization | cell periphery | axon | membrane-enclosed lumen | growth cone | cytosol | cytoskeleton | intracellular | cell junction | membrane | supramolecular complex | protein kinase 5 complex
