QuickView for CFD;jsessionid=78F73C851409D5C2F864F21E98F7DD3E;jsessionid=C38B2AC7CBD1B41146F9E98DF044E3C4 (gene)

Gene Symbol:

Cfd Mus musculus

Full name:

complement factor D (adipsin)

Synonyms:

Adn, DF, complement factor D, 28 kDa adipocyte protein, C3 convertase activator, D component (adipsin) of complement, properdin factor D

Genomic Location:

Chr 10: 79353657-79355399

Description:

This gene encodes a serine protease that plays an important role in the alternative pathway of complement activation for pathogen recognition and elimination. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme that in turn cleaves factor B in the complement pathway. This gene is expressed in adipocyte...

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This gene encodes a serine protease that plays an important role in the alternative pathway of complement activation for pathogen recognition and elimination. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional enzyme that in turn cleaves factor B in the complement pathway. This gene is expressed in adipocytes and the mature enzyme is secreted into the bloodstream. Mice lacking the encoded product cannot initiate alternative pathway of complement activation.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

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