QuickView for COL4A5;jsessionid=8166F85B64BEA17874F926065A88C462;jsessionid=D146C7B0892E4299165FB282F4DEB282;jsessionid=6B29677B355632FADFA3C8AC25CE302E;jsessionid=DFCCCA126E1BCC73F6679F0AD59BBB6C;jsessionid=FA86B5BD2205AA4731118F5CEA6C9E3F (gene)

Gene Symbol:

COL4A5 Homo sapiens

Full name:

collagen type IV alpha 5 chain

Synonyms:

ASLN, ATS, CA54, collagen alpha-5(IV) chain, collagen IV, alpha-5 polypeptide, collagen of basement membrane, alpha-5 chain, collagen, type IV, alpha 5, dA149D17.3, dA24A23.1

Genomic Location:

Chr X: 107569810-107827431

Description:

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another t...

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This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF1_01 ,  TTANTCA_UNKNOWN ,  ATCMNTCCGY_UNKNOWN ,  PBX1_01 ,  WHN_B ,  COMP1_01 ,  GGGAGGRR_MAZ_Q6 ,  RGAANNTTC_HSF1_01 ,  GTGACGY_E4F1_Q6 ,  GGGCGGR_SP1_Q6 ,  OCT1_03 ,  SOX5_01 ,  AATGTGA_MIR23A_MIR23B ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  WGGAATGY_TEF1_Q6 ,  AAAYRNCTG_UNKNOWN ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  HNF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-324-5p ,  Predicted Gene Targets for miR-29

Cytogenetic Map:

Xq22.3

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