QuickView for CP2B;jsessionid=3806AEFFFACCB28A5770FF95CB5E4E9C;jsessionid=F9FB86721E133081CA341F3FEE7D251E;jsessionid=8DAD59C96F12CC1A70C5BD4B4D4665CC;jsessionid=9E029E109AA0821A304B760B8F1DAC78 (gene)
- Gene Symbol:
- Cyp27b1
Rattus norvegicus - Full name:
- cytochrome P450, family 27, subfamily b, polypeptide 1
- Synonyms:
- Cyp40, 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial, 25-OHD-1 alpha-hydroxylase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, P450C1 alpha, P450VD1-alpha, VD3 1A hydroxylase, calcidiol 1-monooxygenase, cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1, cytochrome P450 subfamily XXVIIB polypeptide 1, cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase), cytochrome P450, subfamily 27b, polypeptide 1, cytochrome P450C1 alpha, cytochrome P450VD1-alpha, cytochrome p450 27B1
- Genomic Location:
- N/A
- Description:
-
cytochrome P450 enzyme that plays a role in vitamin D metabolism
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
GO Molecular Function
cofactor binding | calcidiol 1-monooxygenase activity | cation binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity
GO Biological Process
response to extracellular stimulus | response to nutrient levels | response to cytokine | response to lipopolysaccharide | developmental process involved in reproduction | vitamin biosynthetic process | negative regulation of vitamin D biosynthetic process | establishment of localization | response to hormone | negative regulation of cellular process | positive regulation of developmental process | response to metal ion | bone mineralization | regulation of vitamin metabolic process | maternal placenta development | defense response | response to drug | polyol metabolic process | calcidiol 1-monooxygenase activity | response to organophosphorus | cellular process | secretion | organic substance catabolic process | localization | metal ion transport | reproductive system development | female pregnancy | multicellular organismal reproductive process | negative regulation of lipid biosynthetic process | positive regulation of oxidoreductase activity | positive regulation of catalytic activity | response to inorganic substance | negative regulation of cellular metabolic process | regulation of bone mineralization | response to peptide hormone | G1 to G0 transition | tissue development | regulation of cell differentiation | response to prostaglandin | vitamin D3 metabolic process | regulation of cellular process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | steroid biosynthetic process | calcium ion homeostasis | calcitriol biosynthetic process from calciol | response to stimulus | response to stress | positive regulation of epidermal cell differentiation | alcohol metabolic process | positive regulation of vitamin D receptor signaling pathway | regulation of cell proliferation | response to peptide | regulation of epithelial cell differentiation | reproduction | divalent metal ion transport | response to alcohol | response to molecule of bacterial origin | regulation of calcidiol 1-monooxygenase activity | response to vitamin D | negative regulation of metabolic process | regulation of steroid biosynthetic process | cellular biosynthetic process | regulation of steroid metabolic process | metal ion homeostasis | organic hydroxy compound metabolic process | response to nitrogen compound | response to external biotic stimulus | system development | reproductive process | regulation of signal transduction | negative regulation of growth | multicellular organism development | negative regulation of catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | negative regulation of calcidiol 1-monooxygenase activity | hormone biosynthetic process | response to purine-containing compound | mammary gland development | response to fatty acid | regulation of catalytic activity | steroid catabolic process | lipid metabolic process | regulation of hormone levels | regulation of ossification | response to prostaglandin E | response to ketone | response to lipid | cell cycle | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | regulation of epidermis development | regulation of keratinocyte differentiation | small molecule metabolic process | response to nutrient | positive regulation of cell differentiation | biosynthetic process | regulation of hormone metabolic process | lipid biosynthetic process | cation homeostasis | response to bacterium | response to estrogen | regulation of cellular metabolic process | positive regulation of signal transduction | homeostatic process | regulation of lipid biosynthetic process | negative regulation of cell growth | decidualization | drug metabolic process | positive regulation of molecular function | negative regulation of monooxygenase activity | positive regulation of vitamin D 24-hydroxylase activity | multicellular organism reproduction | maternal process involved in female pregnancy | regulation of growth | response to organic substance | gland development | vitamin metabolic process | lactation | response to insulin | anatomical structure development | positive regulation of keratinocyte differentiation | negative regulation of lipid metabolic process | metabolic process | regulation of body fluid levels | oxidation-reduction process | chemical homeostasis | calcium ion transport | body fluid secretion | immune response | lipid catabolic process | organic substance metabolic process | response to copper ion | response to vitamin | negative regulation of biosynthetic process | animal organ development | ion homeostasis | biomineral tissue development | response to interferon-gamma | response to cAMP | regulation of vitamin D receptor signaling pathway | steroid metabolic process | negative regulation of hormone biosynthetic process | regulation of cell communication | negative regulation of molecular function | regulation of oxidoreductase activity | response to organic cyclic compound | vitamin D catabolic process | hormone metabolic process | cation transport | response to biotic stimulus | reproductive structure development | regulation of developmental process | developmental process | negative regulation of steroid metabolic process | regulation of cell growth | positive regulation of epithelial cell differentiation | negative regulation of cell proliferation | innate immune response | negative regulation of oxidoreductase activity | response to organonitrogen compound | positive regulation of epidermis development | response to calcium ion | regulation of lipid metabolic process | positive regulation of metabolic process | ossification | ion transport | immune system process | cellular metabolic process | placenta development | oxidoreductase activity | aging | divalent inorganic cation homeostasis | vitamin D metabolic process | regulation of cellular component organization | negative regulation of steroid biosynthetic process | regulation of epidermal cell differentiation | response to other organism | positive regulation of signaling | regulation of signaling | regulation of hormone biosynthetic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane
