QuickView for CP8B;jsessionid=8CD92FAB3098C740F59BC4C454EE2DA4;jsessionid=15AF24D0886946CA3052B4B6726D38EE (gene)
- Gene Symbol:
- Cyp8b1
Rattus norvegicus - Full name:
- cytochrome P450 family 8 subfamily B member 1
- Synonyms:
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, cytochrome P450, 8b1, sterol 12 alpha-hydrolase, cytochrome P450, family 8, subfamily b, polypeptide 1
- Genomic Location:
- Chr 8: 127018908-127020878
- Description:
-
member of the cytochrome P450 enzyme superfamily; endoplasmic reticulum membrane protein; plays a role in sterol metabolism; human homolog is unique among cytochrome P450 genes in that it is intronless
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | sterol 12-alpha-hydroxylase activity | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity
GO Biological Process
steroid hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | sterol 12-alpha-hydroxylase activity | metabolic process | oxidation-reduction process | oxidoreductase activity
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
