QuickView for CRDGF;jsessionid=76707BEF1A335A7C4FFEBE7A666DEA81;jsessionid=C2AF00D7D6A112051C79AF2EA0D071F3 (gene)
- Gene Symbol:
- Areg
Rattus norvegicus - Full name:
- amphiregulin
- Synonyms:
- amphiregulin, AR, SDGF, schwannoma-derived growth factor
- Genomic Location:
- Chr 14: 18466313-18475571
- Description:
-
may act as a growth factor during central nervous system development
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
CREB_01 , CREBP1CJUN_01 , ATF_B , ATF3_Q6 , ATF1_Q6 , CREB_Q2_01 , CREB_Q4_01 , TGACGTCA_ATF3_Q6 , TGAYRTCA_ATF3_Q6 , TGGAAA_NFAT_Q4_01
GO Molecular Function
signaling receptor binding | molecular function regulator | protein binding | receptor regulator activity | growth factor activity | receptor ligand activity | cytokine activity | epidermal growth factor receptor binding | growth factor receptor binding
GO Biological Process
glial cell proliferation | developmental process involved in reproduction | mammary gland duct morphogenesis | morphogenesis of an epithelium | positive regulation of peptidyl-tyrosine phosphorylation | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis | response to hormone | negative regulation of cellular process | epithelial cell proliferation involved in mammary gland duct elongation | cell differentiation | nervous system development | response to drug | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | response to antibiotic | response to organophosphorus | cellular process | epithelial tube morphogenesis | developmental growth | neuron development | response to estradiol | positive regulation of nitrogen compound metabolic process | response to inorganic substance | response to peptide hormone | tissue development | regulation of cell differentiation | response to hydrogen peroxide | regulation of cellular process | regulation of osteoblast differentiation | regulation of metabolic process | gliogenesis | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | epithelium development | cellular component organization | mammary gland morphogenesis | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | gland morphogenesis | response to stress | regulation of cell proliferation | tube morphogenesis | response to peptide | reproduction | axis elongation | ERBB signaling pathway | G-protein coupled receptor signaling pathway | molecular function regulator | response to nitrogen compound | negative regulation of osteoblast differentiation | system development | reproductive process | regulation of signal transduction | multicellular organism development | response to purine-containing compound | mammary gland development | regulation of phosphorylation | regulation of ossification | mammary gland lobule development | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | response to corticosteroid | response to oxidative stress | cell proliferation | regulation of cellular protein metabolic process | mammary gland epithelial cell proliferation | response to toxic substance | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of cell proliferation | regulation of protein phosphorylation | neuron differentiation | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | response to organic substance | gland development | tissue morphogenesis | branching morphogenesis of an epithelial tube | epithelial cell proliferation | negative regulation of ossification | anatomical structure development | developmental growth involved in morphogenesis | branch elongation of an epithelium | cell surface receptor signaling pathway | growth factor activity | cell projection organization | development of secondary sexual characteristics | receptor ligand activity | development of secondary female sexual characteristics | neuron projection development | cytokine activity | animal organ development | response to reactive oxygen species | mammary gland branching involved in thelarche | regulation of phosphate metabolic process | mammary gland epithelium development | response to cAMP | morphogenesis of a branching epithelium | mammary gland alveolus development | regulation of cell communication | signaling | response to organic cyclic compound | cell development | positive regulation of phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of developmental process | developmental process | branch elongation involved in mammary gland duct branching | tube development | response to organonitrogen compound | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | response to steroid hormone | branching involved in mammary gland duct morphogenesis | negative regulation of cell differentiation | signal transduction | regulation of signaling | response to glucocorticoid | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cell surface | intracellular | membrane
