QuickView for CRH;jsessionid=FC53D48664FD9BE7F519DA25783A5601;jsessionid=8BEE4640FFEA6ACC357CCD241D1806F3;jsessionid=A338F6682E9A34127D91E73B1A783E36;jsessionid=11FF111B3093E0DEFBE9926D8FADBEBA (gene)

Gene Symbol:

Crh Mus musculus

Full name:

corticotropin releasing hormone

Synonyms:

CRF, Gm1347, corticoliberin, corticotropin releasing factor

Genomic Location:

Chr 3: 19593414-19595329

Description:

This gene encodes a member of the corticotropin-releasing factor family and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is a neuropeptide hormone that binds to the corticotropin releasing hormone receptors (CRHR1 and CRHR2) to stimulate the release of adrenocorticotropic hormone from th...

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This gene encodes a member of the corticotropin-releasing factor family and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is a neuropeptide hormone that binds to the corticotropin releasing hormone receptors (CRHR1 and CRHR2) to stimulate the release of adrenocorticotropic hormone from the pituitary gland in response to stress. The encoded protein may also regulate angiogenesis and inflammation. Homozygous knockout mice for this gene exhibit reduced corticosterone levels while the offspring of these mice die perinatally.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAAYRNCTG_UNKNOWN ,  AACTTT_UNKNOWN ,  CREB_01 ,  CREBP1CJUN_01 ,  EVI1_04 ,  CDPCR3_01 ,  CREB_02 ,  HFH1_01 ,  FOXD3_01 ,  SRY_02 ,  OCT1_05 ,  CREB_Q2 ,  CREB_Q4 ,  CREBP1_Q2 ,  CAGNWMCNNNGAC_UNKNOWN ,  AHRARNT_01 ,  HFH3_01 ,  FREAC7_01 ,  HFH8_01 ,  ATF_B ,  TGIF_01 ,  FOXJ2_01 ,  POU6F1_01 ,  FOXO1_01 ,  FOXO4_02 ,  FOXO3_01 ,  ATF3_Q6 ,  HOXA4_Q2 ,  HNF3ALPHA_Q6 ,  HFH4_01 ,  CEBP_Q3 ,  HNF3_Q6 ,  TTF1_Q6 ,  SRF_Q4 ,  CEBP_Q2_01 ,  CREB_Q4_01 ,  SRF_Q5_01 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GCTTGAA_MIR498 ,  TAAYNRNNTCC_UNKNOWN ,  TCCATTKW_UNKNOWN ,  TGTYNNNNNRGCARM_UNKNOWN ,  YATTNATC_UNKNOWN ,  TGACGTCA_ATF3_Q6 ,  TGAYRTCA_ATF3_Q6 ,  GTGACGY_E4F1_Q6 ,  TGACCTY_ERR1_Q2 ,  TTGTTT_FOXO4_01 ,  RTAAACA_FREAC2_01 ,  AAAYWAACM_HFH4_01 ,  CTTTGA_LEF1_Q2 ,  CTTTGT_LEF1_Q2 ,  TGACAGNY_MEIS1_01 ,  TATAAA_TATA_01 ,  TGANNYRGCA_TCF11MAFG_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-200b

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