QuickView for CRHBP;jsessionid=2107FB805BCD959FF6C52E854085270E;jsessionid=CE28F8D20D62875CCDBF2DB2A8242784 (gene)
- Gene Symbol:
- Crhbp
Rattus norvegicus - Full name:
- corticotropin releasing hormone binding protein
- Synonyms:
- Crfbp, corticotropin-releasing factor-binding protein, CRF-BP, CRF-binding protein, CRH-BP
- Genomic Location:
- Chr 2: 25801371-25813430
- Description:
-
binds corticotropin releasing hormone and modulates CRH action; may act as a reservoir of endogenous CRH in the brain
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
peptide binding | peptide hormone binding | neurotransmitter binding | amide binding | hormone binding | corticotropin-releasing hormone binding
GO Biological Process
negative regulation of signaling receptor activity | exocytosis | response to cytokine | negative regulation of peptide secretion | regulation of localization | response to immobilization stress | establishment of localization | response to hormone | negative regulation of cellular process | response to potassium ion | response to metal ion | cellular response to tumor necrosis factor | defense response | response to drug | regulation of peptide hormone secretion | response to antibiotic | hormone-mediated signaling pathway | response to organophosphorus | cellular process | secretion | localization | negative regulation of signaling | chemical synaptic transmission | response to estradiol | female pregnancy | cellular response to potassium ion | negative regulation of secretion | negative regulation of hormone secretion | response to inorganic substance | response to peptide hormone | regulation of cellular process | cellular response to lipid | cellular response to organonitrogen compound | cellular response to metal ion | regulation of peptide secretion | response to stimulus | cellular response to immobilization stress | response to gonadotropin-releasing hormone | response to cocaine | cellular response to xenobiotic stimulus | response to stress | response to peptide | regulation of neurotransmitter receptor activity | reproduction | cellular response to inorganic substance | secretion by cell | response to alcohol | negative regulation of transport | cellular response to organic cyclic compound | regulation of peptide transport | cell-cell signaling | synaptic transmission, dopaminergic | response to ethanol | regulation of cellular response to stress | response to nitrogen compound | cellular response to hormone stimulus | reproductive process | regulation of signal transduction | cellular response to gonadotropin-releasing hormone | negative regulation of secretion by cell | cellular response to peptide hormone stimulus | response to purine-containing compound | regulation of hormone levels | regulation of hormone secretion | cellular response to ammonium ion | cellular response to stress | response to lipid | cellular response to peptide | synaptic signaling | behavioral response to ethanol | response to ammonium ion | aggressive behavior | vesicle-mediated transport | cellular response to alkaloid | cellular response to cytokine stimulus | negative regulation of peptide hormone secretion | regulated exocytosis | response to toxic substance | response to xenobiotic stimulus | maternal aggressive behavior | cellular response to drug | negative regulation of corticotropin secretion | response to estrogen | cell communication | cellular response to estrogen stimulus | inflammatory response | regulation of endocrine process | regulation of signaling receptor activity | cellular response to calcium ion | response to organic substance | metabolic process | regulation of secretion | behavior | cellular response to cAMP | response to alkaloid | regulation of ion transmembrane transport | response to cAMP | cellular response to cocaine | adult behavior | cellular response to estradiol stimulus | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | regulation of corticotropin secretion | signaling | response to organic cyclic compound | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | hormone metabolic process | regulation of NMDA receptor activity | regulation of ion transport | negative regulation of corticotropin-releasing hormone receptor activity | regulation of transport | regulation of cation channel activity | response to organonitrogen compound | regulation of glutamate receptor signaling pathway | response to calcium ion | response to anesthetic | response to tumor necrosis factor | cellular response to organic substance | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
secretory granule | supramolecular fiber | dendrite | intracellular membrane-bounded organelle | synapse | late endosome | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | varicosity | multivesicular body | neuronal cell body | distal axon | microtubule | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | secondary lysosome | main axon | presynapse | Golgi apparatus | cell projection | secretory vesicle | endomembrane system | perikaryon | vacuole | vesicle | dense core granule | microtubule cytoskeleton | lytic vacuole | endosome | extracellular region | membrane-bounded organelle | nucleus | organelle | axon terminus | lysosome | extracellular space | axon | neuron projection terminus | intracellular vesicle | cytoskeleton | intracellular | supramolecular complex
