QuickView for CSE1;jsessionid=2A1230EB55F9C9C2364DE83C89F74058;jsessionid=E62462125AE2B19FA699F043BCEF06B0;jsessionid=71A142B4C775104C625D50EFA7020280;jsessionid=1569BA11B74DAF3E6F1B73296854A84A (gene)
- Gene Symbol:
- CSE1L
Homo sapiens - Full name:
- chromosome segregation 1 like
- Synonyms:
- CAS, CSE1, XPO2, exportin-2, CSE1 chromosome segregation 1-like, cellular apoptosis susceptibility protein, chromosome segregation 1-like protein, exp2, importin-alpha re-exporter
- Genomic Location:
- Chr 20: 47096245-47146893
- Description:
-
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
20q13.13
GO Molecular Function
GTPase binding | enzyme binding | protein transporter activity | Ras GTPase binding | transporter activity | nuclear export signal receptor activity | protein binding | Ran GTPase binding | small GTPase binding
GO Biological Process
nuclear export | establishment of localization | intracellular transport | cellular process | localization | protein transport | macromolecule localization | establishment of localization in cell | protein import into nucleus | protein transporter activity | protein export from nucleus | intracellular protein transport | protein localization to nucleus | programmed cell death | cellular localization | apoptotic process | organic substance transport | peptide transport | protein localization to organelle | import into nucleus | cell proliferation | nuclear export signal receptor activity | protein import | establishment of protein localization to organelle | cellular protein localization | amide transport | nuclear transport | cell death | establishment of protein localization | protein localization | cellular macromolecule localization | nucleocytoplasmic transport
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | endomembrane system | nucleoplasm | nuclear envelope | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | cytosol | intracellular | membrane
