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QuickView for CXCL1;jsessionid=22A1656291A63C56023A2B07346CC8CB;jsessionid=78D9A1207DFA2150D9C50356144BAF69 (gene)


Gene Symbol:
Cxcl1 Mus musculus Mus musculus
Full name:
chemokine (C-X-C motif) ligand 1
Synonyms:
Fsp, Gro1, KC, Mgsa, N51, Scyb1, gro, growth-regulated alpha protein, C-X-C motif chemokine 1, GRO1 oncogene, KC/GR)-alpha, KC/GRO-alpha, alpha-chemokine, platelet-derived growth factor-inducible protein KC, secretory protein N51
Genomic Location:
Chr 5: 91320336-91322141
Description:
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, d...
Orthologs:
Homo sapiens Rattus norvegicus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_008176
Protein Names
A2RTH0
P12850



GO Molecular Function

chemokine activity | signaling receptor binding | cytokine receptor binding | molecular function regulator | chemokine receptor binding | protein binding | receptor regulator activity | growth factor activity | G-protein coupled receptor binding | receptor ligand activity | cytokine activity

GO Biological Process

positive regulation of cell killing | response to cytokine | cell motility | response to lipopolysaccharide | regulation of localization | regulation of sodium ion transport | regulation of immune system process | positive regulation of developmental process | chemokine-mediated signaling pathway | defense response | cellular chemical homeostasis | regulation of leukocyte mediated cytotoxicity | regulation of defense response to fungus | regulation of neutrophil mediated cytotoxicity | cellular process | localization | cellular homeostasis | positive regulation of immune effector process | chemokine activity | positive regulation of reactive oxygen species metabolic process | positive regulation of killing of cells of other organism | granulocyte chemotaxis | regulation of cellular process | cellular response to lipid | regulation of metabolic process | regulation of cytosolic calcium ion concentration | cellular response to molecule of bacterial origin | positive regulation of potassium ion transport | calcium ion homeostasis | response to stimulus | neutrophil chemotaxis | positive regulation of immune system process | response to stress | regulation of cell proliferation | regulation of hematopoietic stem cell proliferation | positive regulation of superoxide anion generation | response to molecule of bacterial origin | cell chemotaxis | molecular function regulator | metal ion homeostasis | leukocyte migration | locomotion | regulation of superoxide metabolic process | response to external biotic stimulus | regulation of signal transduction | cell migration | regulation of killing of cells of other organism | response to lipid | regulation of stem cell proliferation | positive regulation of cellular metabolic process | cellular ion homeostasis | positive regulation of neutrophil mediated killing of fungus | positive regulation of cytosolic calcium ion concentration | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | cation homeostasis | response to bacterium | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | antimicrobial humoral immune response mediated by antimicrobial peptide | humoral immune response | inflammatory response | leukocyte chemotaxis | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | positive regulation of transport | regulation of potassium ion transport | regulation of signaling receptor activity | antimicrobial humoral response | receptor regulator activity | response to organic substance | positive regulation of hematopoietic stem cell proliferation | regulation of hemopoiesis | cell surface receptor signaling pathway | growth factor activity | chemical homeostasis | receptor ligand activity | immune response | cytokine activity | positive regulation of ion transport | positive regulation of sodium ion transport | ion homeostasis | regulation of cell communication | signaling | positive regulation of stem cell proliferation | response to biotic stimulus | regulation of developmental process | regulation of ion transport | regulation of transport | regulation of reactive oxygen species metabolic process | positive regulation of leukocyte mediated cytotoxicity | regulation of superoxide anion generation | cellular metal ion homeostasis | positive regulation of metabolic process | acute inflammatory response | immune system process | cellular response to organic substance | neutrophil migration | chemotaxis | divalent inorganic cation homeostasis | response to other organism | signal transduction | regulation of signaling | cellular response to lipopolysaccharide

GO Cellular Component

extracellular region | extracellular space