QuickView for CYP11A;jsessionid=1A820183BB627AF461261873C6003289;jsessionid=D5E0A53773C7629D90939051E2562DA0 (gene)
- Gene Symbol:
- Cyp11a1
Rattus norvegicus - Full name:
- cytochrome P450, family 11, subfamily a, polypeptide 1
- Synonyms:
- Cyp11a, Cypxia1, P450(scc), P450scc, cholesterol side-chain cleavage enzyme, mitochondrial, cholesterol desmolase, cholesterol side-chain cleavage cytochrome P450, cytochrome P450 11A1, cytochrome P450 11a cholesterol side chain cleavage, cytochrome P450 family 11 subfamily a, cytochrome P450 side-chain cleavage enzyme, cytochrome P450 subfamily 11A, cytochrome P450(scc)
- Genomic Location:
- Chr 8: 61793933-61805482
- Description:
-
monooxygenase that catalyzes synthesis of cholesterol and steroids
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | steroid hydroxylase activity | lipid binding | sterol binding | iron ion binding | alcohol binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | cholesterol binding | tetrapyrrole binding | cholesterol monooxygenase (side-chain-cleaving) activity | transition metal ion binding | heme binding | steroid binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
response to extracellular stimulus | brain development | response to radiation | response to nutrient levels | response to cytokine | response to interleukin-1 | response to lipopolysaccharide | developmental process involved in reproduction | gonad development | Schwann cell differentiation | hippocampus development | response to hormone | response to hydroxyisoflavone | response to metal ion | cellular response to tumor necrosis factor | cell differentiation | nervous system development | response to drug | benzene-containing compound metabolic process | neurogenesis | response to antibiotic | phenol-containing compound metabolic process | response to organophosphorus | sterol metabolic process | cellular process | Leydig cell differentiation | peripheral nervous system development | dicarboxylic acid metabolic process | reproductive system development | female pregnancy | multicellular organismal reproductive process | response to corticosterone | response to growth factor | response to inorganic substance | response to peptide hormone | tissue development | response to hydrogen peroxide | cellular response to lipid | gliogenesis | xenobiotic metabolic process | steroid hydroxylase activity | cellular response to molecule of bacterial origin | organic cyclic compound metabolic process | epithelium development | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | steroid biosynthetic process | response to transforming growth factor beta | cellular response to metal ion | development of primary sexual characteristics | head development | response to stimulus | cellular response to fibroblast growth factor stimulus | metencephalon development | response to salt stress | cellular response to xenobiotic stimulus | response to stress | alcohol metabolic process | response to peptide | reproduction | cellular response to inorganic substance | response to alcohol | cellular response to cadmium ion | response to molecule of bacterial origin | cellular response to organic cyclic compound | cellular biosynthetic process | response to phenylpropanoid | granulosa cell differentiation | organic hydroxy compound metabolic process | response to nitrogen compound | cellular response to hormone stimulus | response to external biotic stimulus | system development | reproductive process | cellular response to antibiotic | multicellular organism development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | antibiotic metabolic process | cellular response to peptide hormone stimulus | response to amino acid | hormone biosynthetic process | response to purine-containing compound | response to follicle-stimulating hormone | response to vitamin E | cerebellum development | lipid metabolic process | regulation of hormone levels | telencephalon development | response to ketone | response to lipid | cellular response to peptide | cellular response to gonadotropin stimulus | dibenzo-p-dioxin metabolic process | small molecule metabolic process | response to corticosteroid | response to nutrient | response to oxidative stress | cellular response to cytokine stimulus | cellular ketone metabolic process | biosynthetic process | response to cadmium ion | response to osmotic stress | phthalate metabolic process | glial cell differentiation | hindbrain development | lipid biosynthetic process | response to toxic substance | testosterone biosynthetic process | response to xenobiotic stimulus | response to gamma radiation | response to bacterium | response to estrogen | limbic system development | response to monosaccharide | response to insecticide | drug metabolic process | carboxylic acid metabolic process | response to genistein | cellular response to transforming growth factor beta stimulus | multicellular organism reproduction | maternal process involved in female pregnancy | development of primary male sexual characteristics | response to organic substance | male sex differentiation | response to antineoplastic agent | biphenyl metabolic process | anatomical structure development | reproductive behavior | metabolic process | response to mineralocorticoid | cholesterol metabolic process | oxidation-reduction process | cholesterol monooxygenase (side-chain-cleaving) activity | male gonad development | mating behavior | behavior | organic substance metabolic process | mating | response to vitamin | animal organ development | response to reactive oxygen species | forebrain development | pallium development | C21-steroid hormone metabolic process | cellular response to cAMP | response to alkaloid | response to L-ascorbic acid | response to gonadotropin | response to cAMP | cellular response to follicle-stimulating hormone stimulus | response to fungicide | steroid metabolic process | glucocorticoid metabolic process | response to organic cyclic compound | organic acid metabolic process | hormone metabolic process | response to biotic stimulus | reproductive structure development | developmental process | cellular response to interleukin-1 | C21-steroid hormone biosynthetic process | glucocorticoid biosynthetic process | response to fibroblast growth factor | response to organonitrogen compound | epithelial cell differentiation | heterocycle metabolic process | central nervous system development | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | sex differentiation | response to carbohydrate | oxidoreductase activity | response to steroid hormone | sexual reproduction | response to ionizing radiation | response to other organism | response to glucocorticoid | cellular response to growth factor stimulus | cellular response to lipopolysaccharide | multicellular organismal process
GO Cellular Component
organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | somatodendritic compartment | organelle membrane | cell body | cell | neuronal cell body | cytoplasm | intracellular organelle | mitochondrial crista | perikaryon | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane
