QuickView for CYP21A1P;jsessionid=AF6443BD12AEE6F6233A3E400C005B27;jsessionid=8E16A09020B275868466A2F50280A8DE (gene)
- Gene Symbol:
- Cyp21a1
Rattus norvegicus - Full name:
- cytochrome P450, family 21, subfamily a, polypeptide 1
- Synonyms:
- 21-OH, Cyp21, steroid 21-hydroxylase, 21-OHase, Cytochrome P450 subfamily XXI (steroid 21-hydroxylase), P-450c21, P450-C21, cytochrome P-450c21, cytochrome P450 21 steroid 21 hydroxylase, cytochrome P450 XXI, cytochrome P450, subfamily 21A, polypeptide 1, cytochrome P450, subfamily XXI (steroid 21-hydroxylase), cytochrome P450-C21
- Genomic Location:
- Chr 20: 4125357-4128518
- Description:
-
converts progesterone to deoxycorticosterone via 21-hydroxylation in the adrenal gland and possibly in peripheral astrocytes and CNS
- Orthologs:
- Homo sapiens , Mus musculus , Pan troglodytes
- External Links:
- Entrez Gene
GO Molecular Function
cofactor binding | cation binding | steroid 21-monooxygenase activity | steroid hydroxylase activity | lipid binding | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | tetrapyrrole binding | transition metal ion binding | heme binding | steroid binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity
GO Biological Process
response to hormone | response to antibiotic | cellular process | response to peptide hormone | steroid 21-monooxygenase activity | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular response to organonitrogen compound | steroid biosynthetic process | response to stimulus | response to peptide | cellular biosynthetic process | response to nitrogen compound | cellular response to hormone stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | cellular response to peptide hormone stimulus | hormone biosynthetic process | lipid metabolic process | regulation of hormone levels | cellular response to peptide | small molecule metabolic process | cellular ketone metabolic process | biosynthetic process | lipid biosynthetic process | mineralocorticoid biosynthetic process | drug metabolic process | response to organic substance | progesterone metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | C21-steroid hormone metabolic process | steroid metabolic process | hormone metabolic process | C21-steroid hormone biosynthetic process | response to organonitrogen compound | cellular metabolic process | cellular response to organic substance | oxidoreductase activity
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
