QuickView for Cdh5;jsessionid=796E5664BAB08D2FDAAF55A63F046A00;jsessionid=40F321DE2164B1F8575F1976C8DDD6D4 (gene)

Gene Symbol:

Cdh5 Mus musculus

Full name:

cadherin 5

Synonyms:

7B4, AA408225, Cd144, VE-Cad, VECD, VEcad, Vec, cadherin-5, 7B4/cadherin-5, VE-cadherin, vascular endothelial cadherin

Genomic Location:

Chr 8: 106625599-106668401

Description:

This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein die in utero due to vascular insufficiency, caused by increased endot...

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This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein die in utero due to vascular insufficiency, caused by increased endothelial apoptosis. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Bos taurus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACTTT_UNKNOWN ,  IK2_01 ,  ARGGGTTAA_UNKNOWN ,  NFKB_C ,  CAGNYGKNAAA_UNKNOWN ,  LMO2COM_02 ,  ETS2_B ,  MSX1_01 ,  E12_Q6 ,  MYOGENIN_Q6 ,  ELF1_Q6 ,  GGGYGTGNY_UNKNOWN ,  ACTGTGA_MIR27A_MIR27B ,  GTACTGT_MIR101 ,  RNGTGGGC_UNKNOWN ,  TGGNNNNNNKCCAR_UNKNOWN ,  TGANTCA_AP1_C ,  RYTTCCTG_ETS2_B ,  TTGTTT_FOXO4_01 ,  CTTTGT_LEF1_Q2 ,  TGGAAA_NFAT_Q4_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-143 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-27

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