QuickView for Chek1;jsessionid=C74665915B02EC76E32048C6D57CE625;jsessionid=DFEE26EB516E23DF1D2363857E04F79C (gene)
- Gene Symbol:
- chk1
Schizosaccharomyces pombe - Full name:
- Chk1 protein kinase
- Synonyms:
- rad27, SPCC1259.13
- Genomic Location:
- Chr III: 1060020-1061775
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of cell cycle process | intracellular signal transduction | negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling | regulation of meiotic cell cycle | negative regulation of cellular process | signal transduction involved in mitotic G2 DNA damage checkpoint | meiotic recombination checkpoint | negative regulation of RNA biosynthetic process | response to DNA damage checkpoint signaling | regulation of organelle organization | negative regulation of meiotic cell cycle | cellular process | localization | mitotic DNA integrity checkpoint | negative regulation of nucleic acid-templated transcription | macromolecule localization | regulation of cell cycle | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | DNA replication checkpoint | cellular aromatic compound metabolic process | signal transduction involved in mitotic DNA damage checkpoint | regulation of G2/M transition of mitotic cell cycle | response to stimulus | regulation of mitotic cell cycle phase transition | response to stress | negative regulation of G2/M transition of mitotic cell cycle | mitotic G2 DNA damage checkpoint | regulation of cell cycle phase transition | protein serine/threonine kinase activity | reproduction | cellular localization | cellular nitrogen compound metabolic process | mitotic DNA replication checkpoint | negative regulation of metabolic process | protein modification process | macromolecule modification | DNA repair | regulation of nucleic acid-templated transcription | regulation of cell cycle G2/M phase transition | nitrogen compound metabolic process | reproductive process | negative regulation of mitotic cell cycle phase transition | mitotic DNA damage checkpoint | negative regulation of cell cycle G2/M phase transition | phosphorus metabolic process | cellular response to DNA damage stimulus | negative regulation of meiotic nuclear division | signal transduction in response to DNA damage | regulation of gene expression | cellular response to stress | cell cycle | regulation of nitrogen compound metabolic process | phosphorylation | meiotic cell cycle checkpoint | signal transduction involved in cell cycle checkpoint | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of RNA metabolic process | regulation of mitotic cell cycle | mitotic G2/M transition checkpoint | protein metabolic process | regulation of meiotic nuclear division | DNA metabolic process | mitotic cell cycle | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of mitotic cell cycle | cellular protein localization | nucleobase-containing compound metabolic process | signal transduction involved in G2 DNA damage checkpoint | protein kinase activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | signal transduction involved in mitotic cell cycle checkpoint | negative regulation of cell cycle | meiotic cell cycle | signaling | regulation of transcription, DNA-templated | protein localization | cellular protein metabolic process | cellular macromolecule localization | signal transduction involved in DNA damage checkpoint | response to biotic stimulus | kinase activity | cellular protein modification process | heterocycle metabolic process | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | DNA damage checkpoint | cell cycle checkpoint | regulation of cellular component organization | signal transduction | negative regulation of transcription by transcription factor localization | macromolecule metabolic process
GO Cellular Component
site of DNA damage | chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | chromatin | nuclear chromosome | site of double-strand break | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | cytosol | intracellular
