QuickView for CstF64;jsessionid=3831563786F97B0B0A9696DC4AAE6D4C;jsessionid=39B7F605AACB165DFD49B69030E59A27;jsessionid=6FC0C92E591DF44D781ED827BF96C6A4;jsessionid=5F2902A1A25E477AB37F91E9A46FED78 (gene)
- Gene Symbol:
- CSTF2
Homo sapiens - Full name:
- cleavage stimulation factor subunit 2
- Synonyms:
- CstF-64, cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, CSTF 64 kDa subunit, betaCstF-64 variant 2, cleavage stimulation factor 64 kDa subunit, cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD, cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
- Genomic Location:
- Chr X: 99962004-99982580
- Description:
-
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
Xq22.1
GO Molecular Function
nucleic acid binding | mRNA binding | organic cyclic compound binding | protein binding | heterocyclic compound binding | RNA binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | RNA processing | mRNA cleavage | cellular process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | RNA splicing | RNA splicing, via transesterification reactions | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | termination of RNA polymerase II transcription | nucleic acid phosphodiester bond hydrolysis | mRNA metabolic process | cellular biosynthetic process | mRNA polyadenylation | RNA polyadenylation | nitrogen compound metabolic process | biosynthetic process | aromatic compound biosynthetic process | DNA-templated transcription, termination | metabolic process | RNA 3'-end processing | nucleobase-containing compound metabolic process | organic substance metabolic process | RNA phosphodiester bond hydrolysis | gene expression | transcription, DNA-templated | cellular macromolecule biosynthetic process | heterocycle metabolic process | mRNA 3'-end processing | cellular metabolic process | pre-mRNA cleavage required for polyadenylation | mRNA processing | mRNA splicing, via spliceosome | mRNA cleavage involved in mRNA processing | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | mRNA cleavage factor complex | cell | nuclear lumen | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | mRNA cleavage and polyadenylation specificity factor complex | cleavage body | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
