QuickView for DGK;jsessionid=DD1AC81602B2BCF3533D693697419DA5;jsessionid=01AC00F63E418DE9ACA05EAC91E4745A (gene)

Gene Symbol:

DGKB Homo sapiens

Full name:

diacylglycerol kinase beta

Synonyms:

DAGK2, DGK, DGK-BETA, diacylglycerol kinase beta, 90 kDa diacylglycerol kinase, DAG kinase beta, diacylglycerol kinase, beta 90kDa, diglyceride kinase beta

Genomic Location:

Chr 7: 14153770-14847413

Description:

Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domai...

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Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_01 ,  TGANTCA_AP1_C ,  YTATTTTNR_MEF2_02 ,  CDP_02 ,  CATTTCA_MIR203 ,  ACCAAAG_MIR9 ,  CDPCR1_01 ,  AAAYRNCTG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  CDC5_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-143 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-495

Cytogenetic Map:

7p21.2

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