QuickView for DIDO1;jsessionid=098A2AD3687F3A1F0E9E1A54AD03E235;jsessionid=70A311BE761669429889AB2B15B629E8;jsessionid=0FD57DA05DED354D78C564817C0573C4 (gene)

Gene Symbol:

Dido1 Mus musculus

Full name:

death inducer-obliterator 1

Synonyms:

6720461J16Rik, D130048F08Rik, DATF-1, DIO-1, Datf1, dido, death-inducer obliterator 1, death inducer-obliterator-2, death inducer-obliterator-3, death-associated transcription factor 1

Genomic Location:

Chr 2: 180392669-180444704

Description:

This gene encodes a transcription factor involved in apoptosis. The encoded protein functions in cell cycle progression and plays a role in chromosomal stability. This protein regulates the self-renewal of embryonic stem cells. Disruption of this gene in mice causes symptoms similar to myelodysplastic/myeloproliferative diseases in humans. Mice lac...

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This gene encodes a transcription factor involved in apoptosis. The encoded protein functions in cell cycle progression and plays a role in chromosomal stability. This protein regulates the self-renewal of embryonic stem cells. Disruption of this gene in mice causes symptoms similar to myelodysplastic/myeloproliferative diseases in humans. Mice lacking this gene show severely reduced fertility. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAAYRNCTG_UNKNOWN ,  AGCYRWTTC_UNKNOWN ,  CTTTAAR_UNKNOWN ,  CCCAGAG_MIR326 ,  TGGAAA_NFAT_Q4_01 ,  RCGCANGCGY_NRF1_Q6

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